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SNP data from Neuroblastoma samples

GSE12494 Homo sapiens Genome variation profiling by SNP array 262 samples Submitted 2008/10/10 Platform GPL2005Platform GPL3718Platform GPL2004
Summary
Neuroblastoma in advanced stages is among the most intractable pediatric cancers, even with the recent therapeutic advances. Neruroblastoma harbours a variety of genetic changes, including a high frequency of MYCN amplification, loss of heterozygosity in 1p36 and 11q, and gain of genetic material from 17q, all of which have been implicated in the pathogenesis of neuroblastoma. However, the scarcity of reliable molecular targets has hampered the development of effective therapeutic agents targeting neuroblastoma. We performed a genome-wide analysis of a large number of neuroblastoma samples, consisting of varying disease stages, permitted us to obtain a comprehensive registry of genomic lesions in neuroblastoma.
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Direct links to NCBI, no account and no request form: the whole study as GSE12494_RAW.tar, processed values as the series matrix, the supplementary file directory, and per-sample supplementary files for any of the 262 samples.

Also filed as BioProject PRJNA112975. Searching any of these in the dataset finder brings you back here.

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