Global skin gene expression profile of early diffuse cutaneous systemic sclerosis shows a prominent innate and adaptive immunity profile
RNA-seq (gene expression) · human · 91 samples
- What it is
- RNA-seq (gene expression)Gene activity measured by sequencing. The summary does not mention single-cell work, so this is most likely bulk: one average per sample, the usual starting point for comparing groups.
- Organism
- Homo sapiens (human)
- Samples
- 91 samples
- Data you can get
- A processed table (series matrix) and supplementary files from NCBI; the raw sequencing reads from ENA. Which of these hold counts depends on the study, so check the file list.
Direct links to NCBI and ENA, no account and no request form. Pick by what you want to do: take the small processed table to look, the supplementary files to re-analyse, or the original raw data to start over.
Processed table
The series matrix: one table of values per sample as the submitters processed it. The smallest download, and it opens in Excel or R. Start here to see what the data look like.
Supplementary files
The count tables and other files the authors uploaded. Take only the samples you need, or the whole study as GSE130955_RAW.tar (it can run to tens of gigabytes).
Raw sequencing reads
The original FASTQ files, straight from the sequencer, held at ENA. Large, and you align them yourself, so only choose this if you need to re-process the study from scratch.
What the files usually look like: For RNA-seq the counts are usually a table among the supplementary files (look for 'counts', 'expression', 'FPKM' or 'TPM' in the file name). The series matrix of a sequencing study is sometimes nearly empty.
Also filed as BioProject PRJNA542095 and SRA study SRP197303. Searching any of these in the dataset finder brings you back here.
The sample list for this study is not cached yet. Press Load samples and it will be fetched from NCBI.
+ 91 more — browse all 91 samples with per-sample file links →
- GSE295274 Cellular and molecular dysregulation of the esophageal epithelium in systemic sclerosis 37 samples shares sclerosis, systemic
- GSE317056 Sex disparity in systemic sclerosis-associated pulmonary fibrosis. 24 samples shares sclerosis, systemic
- GSE292979 Characterisation of a pathogenic non-migratory fibroblast population in systemic sclerosis skin [scRNA-Seq] 15 samples shares sclerosis, systemic
- GSE292702 Characterisation of a pathogenic non-migratory fibroblast population in systemic sclerosis skin 12 samples shares sclerosis, systemic
- GSE320020 Macrophage–Fibroblast Signaling Network Identified by Single-Cell RNA Sequencing in Juvenile Systemic Sclerosis 11 samples shares sclerosis, systemic
- GSE308096 Research on the Pathogenesis of Systemic Sclerosis 20 samples shares sclerosis, systemic
- GSE332819 Longitudinal CITE-seq analysis in juvenile-onset systemic sclerosis monocytes following autologous stem cell transplant 15 samples shares sclerosis, systemic
- GSE267348 Deficiency of lymphatic ERG and FLI1 in systemic sclerosis is associated with rarefaction of skin blood and lymphatic vasculature 12 samples shares sclerosis, systemic
Metadata from NCBI GEO, cached and refreshed periodically — the NCBI page above is authoritative. Downloads link straight to NCBI/ENA; nothing is proxied through BioTransfer.