GEO series

Age-related gene expression changes in mouse neocortex

GSE13120 Mus musculus Expression profiling by array 10 samples Submitted 2008/11/26 Platform GPL1261

Summary

Aging is associated with major nuclear changes affecting genomic integrity and gene expression. Here we compare the gene expression profiles in the neocortex of young (5 months old) and old (30 months old) B6xC3 F1 mice. In a related study, we compare genes that change expression with age to SIRT1 associated genes identified by ChIP on chip (NimbleGen) and find a significant overlap, indicating that SIRT1 target genes are preferentially deregulated with age. Keywords: gene expression comparison, age-comparison

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Direct links to NCBI, no account and no request form: the whole study as GSE13120_RAW.tar, processed values as the series matrix, the supplementary file directory, and per-sample supplementary files for any of the 10 samples.

Whole study · RAW.tar ↓ Series matrix ↓ All supplementary files ↗

Also filed as BioProject PRJNA114119. Searching any of these in the dataset finder brings you back here.

NCBI GEO page ↗ Paper (PMID 19041753) ↗

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