← BioTransfer GEO Dataset Finder
GEO series

Genome wide expression analysis of the effect of senescence associated transcription factor knockdown upon the transcription of senescent cells.

GSE146578 Homo sapiens Expression profiling by high throughput sequencing 9 samples Submitted 2025/05/30 Platform GPL16791
Summary
Senescence associated transcription factors were stably knocked down in senescent BJ fibroblasts, which were then profiled by RNA-seq.
Published in
Ligand-specific regulation of a binary enhancer code dictating cellular senescence
Suter T, Friedman MJ, Tazearslan C et al. · Proceedings of the National Academy of Sciences of the United States of America 2025 · PMID 40493192 · doi:10.1073/pnas.2506321122
This dataset
Download

Direct links to NCBI, no account and no request form: the whole study as GSE146578_RAW.tar, processed values as the series matrix, the supplementary file directory, and per-sample supplementary files for any of the 9 samples. Raw sequencing reads are also available from ENA.

Also filed as BioProject PRJNA610887 and SRA study SRP251908. Searching any of these in the dataset finder brings you back here.

Samples in this study

The sample list for this study is not cached yet. Press Sort into groups and it will be fetched from NCBI.

+ 9 more — browse all 9 samples with per-sample file links →

Similar datasets

Search all human RNA-seq datasets in GEO →

Share this dataset

Metadata from NCBI GEO, cached and refreshed periodically — the NCBI page above is authoritative. Downloads link straight to NCBI/ENA; nothing is proxied through BioTransfer.