G-CSF SECRETED BY EPIGENETICALLY REPROGRAMMED MUTANT IDH1 GLIOMA STEM CELLS, REVERSES THE MYELOID CELLS'-MEDIATED IMMUNOSUPPRESSIVE TUMOR MICROENVIRONMENT
RNA-seq (gene expression) · human · 30 samples
- What it is
- RNA-seq (gene expression)Gene activity measured by sequencing. The summary does not mention single-cell work, so this is most likely bulk: one average per sample, the usual starting point for comparing groups.
- Organism
- Homo sapiens (human)
- Samples
- 30 samples
- Data you can get
- A processed table (series matrix) and supplementary files from NCBI; the raw sequencing reads from ENA. Which of these hold counts depends on the study, so check the file list.
Direct links to NCBI and ENA, no account and no request form. Pick by what you want to do: take the small processed table to look, the supplementary files to re-analyse, or the original raw data to start over.
Processed table
The series matrix: one table of values per sample as the submitters processed it. The smallest download, and it opens in Excel or R. Start here to see what the data look like.
Supplementary files
The count tables and other files the authors uploaded. Take only the samples you need, or the whole study as GSE152277_RAW.tar (it can run to tens of gigabytes).
Raw sequencing reads
The original FASTQ files, straight from the sequencer, held at ENA. Large, and you align them yourself, so only choose this if you need to re-process the study from scratch.
What the files usually look like: For RNA-seq the counts are usually a table among the supplementary files (look for 'counts', 'expression', 'FPKM' or 'TPM' in the file name). The series matrix of a sequencing study is sometimes nearly empty.
Also filed as BioProject PRJNA638878 and SRA study SRP266929. Searching any of these in the dataset finder brings you back here.
The sample list for this study is not cached yet. Press Load samples and it will be fetched from NCBI.
+ 30 more — browse all 30 samples with per-sample file links →
- GSE268118 Mutant IDH modulates suppressive myeloid populations in malignant glioma 34 samples shares myeloid, mutant, glioma
- GSE274229 Evolution of myeloid-mediated immunotherapy resistance in prostate cancer 52 samples shares mediated, myeloid
- GSE304030 oHSV-mediated JAG1 blockade induces glioma senescence-associated secretory phenotype to increase macrophage activation and sensitize to cetuximab-mediated senolysis 24 samples shares mediated, glioma
- GSE326006 Convection-enhanced delivery of dexamethasone in glioma models suppresses myeloid inflammation while avoiding systemic toxicities 21 samples shares myeloid, glioma
- GSE255330 Myeloid progenitor dysregulation fuels immunosuppressive macrophages in tumors [dataset 1] 65 samples shares myeloid, tumor
- GSE172333 A myeloid maturation program initiated by nucleotide depletion during S phase [RNA-Seq] 158 samples shares myeloid
- GSE279626 PGLYRP-1 mediated intracellular peptidoglycan detection promotes mucosal protection 82 samples shares mediated
- GSE244945 NOTCH1 reverses immune suppression in small cell lung cancer through reactivation of STING [RNA-seq] 69 samples shares reverses
Metadata from NCBI GEO, cached and refreshed periodically — the NCBI page above is authoritative. Downloads link straight to NCBI/ENA; nothing is proxied through BioTransfer.