PGLYRP-1 mediated intracellular peptidoglycan detection promotes mucosal protection
RNA-seq (gene expression) · human · 82 samples
- What it is
- RNA-seq (gene expression)Gene activity measured by sequencing. The summary does not mention single-cell work, so this is most likely bulk: one average per sample, the usual starting point for comparing groups.
- Organism
- Homo sapiens (human)
- Samples
- 82 samples: 21 conditions, mostly in triplicateGroups are read from the sample names, not from the paper. Check the list below.
- Data you can get
- A processed table (series matrix) and supplementary files from NCBI; the raw sequencing reads from ENA. Which of these hold counts depends on the study, so check the file list.
- Paper
- PGLYRP1-mediated intracellular peptidoglycan detection promotes intestinal mucosal protectionNature communications · 2025
Read the full summary ↓
Direct links to NCBI and ENA, no account and no request form. Pick by what you want to do: take the small processed table to look, the supplementary files to re-analyse, or the original raw data to start over.
Processed table
The series matrix: one table of values per sample as the submitters processed it. The smallest download, and it opens in Excel or R. Start here to see what the data look like.
Supplementary files
The count tables and other files the authors uploaded. Take only the samples you need, or the whole study as GSE279626_RAW.tar (it can run to tens of gigabytes).
Raw sequencing reads
The original FASTQ files, straight from the sequencer, held at ENA. Large, and you align them yourself, so only choose this if you need to re-process the study from scratch.
What the files usually look like: For RNA-seq the counts are usually a table among the supplementary files (look for 'counts', 'expression', 'FPKM' or 'TPM' in the file name). The series matrix of a sequencing study is sometimes nearly empty.
Also filed as BioProject PRJNA1173729 and SRA study SRP538952. Searching any of these in the dataset finder brings you back here.
Supports a between-group comparison across 54 samples.
How we read this: 21 replicated groups read from 82 sample titles; they account for 54 of them. These groups are guessed from the sample names, not taken from the paper, so check them against the sample list below before relying on them.
- GSM8577181 WT-UT-1 WT-UT
- GSM8577182 WT-UT-2 WT-UT
- GSM8577183 WT-MDP-1 WT-MDP
- GSM8577184 WT-MDP-2 WT-MDP
- GSM8577185 WT-GMTP-1 WT-GMTP
- GSM8577186 WT-GMTP-2 WT-GMTP
- GSM8577188 PG1-0-1 PG1-0
- GSM8577189 PG1-0-2 PG1-0
- GSM8577191 PG1-MDP-1 PG1-MDP
- GSM8577192 PG1-MDP-2 PG1-MDP
- GSM8577194 PG1-GMTP-1 PG1-GMTP
- GSM8577195 PG1-GMTP-2 PG1-GMTP
- GSM8577197 NOD2-UT-1 NOD2-UT
- GSM8577198 NOD2-UT-2 NOD2-UT
- GSM8577199 NOD2-MDP-1 NOD2-MDP
- GSM8577200 NOD2-MDP-2 NOD2-MDP
- GSM8577201 NOD2-GMTP-1 NOD2-GMTP
- GSM8577202 NOD2-GMTP-2 NOD2-GMTP
- GSM8577203 NOD2-0-1 NOD2-0
- GSM8577204 NOD2-0-2 NOD2-0
- GSM8577205 NOD2-0-3 NOD2-0
- GSM8577206 NOD2-G-1 NOD2-G
- GSM8577207 NOD2-G-2 NOD2-G
- GSM8577208 NOD2-G-3 NOD2-G
- GSM8577209 NOD2-M-1 NOD2-M
- GSM8577210 NOD2-M-2 NOD2-M
- GSM8577211 NOD2-M-3 NOD2-M
- GSM8577212 Pglyrp1-0-1 Pglyrp1-0
- GSM8577213 Pglyrp1-0-2 Pglyrp1-0
- GSM8577214 Pglyrp1-0-3 Pglyrp1-0
- GSM8577215 Pglyrp1--G-1 Pglyrp1--G
- GSM8577216 Pglyrp1--G-2 Pglyrp1--G
- GSM8577217 Pglyrp1--G-3 Pglyrp1--G
- GSM8577218 Pglyrp1-M-1 Pglyrp1-M
- GSM8577219 Pglyrp1-M-2 Pglyrp1-M
- GSM8577220 Pglyrp1-M-3 Pglyrp1-M
- GSM8577221 WT-0-1 WT-0
- GSM8577222 WT-0-2 WT-0
- GSM8577223 WT-0-3 WT-0
- GSM8577224 WT-G-1 WT-G
+ 42 more — browse all 82 samples with per-sample file links →
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Metadata from NCBI GEO, cached and refreshed periodically — the NCBI page above is authoritative. Downloads link straight to NCBI/ENA; nothing is proxied through BioTransfer.