Neoadjuvant Intense ADT for High Risk Prostate Cancer: Baseline Analysis
RNA-seq (gene expression) · human · 142 samples
- What it is
- RNA-seq (gene expression)Gene activity measured by sequencing. The summary does not mention single-cell work, so this is most likely bulk: one average per sample, the usual starting point for comparing groups.
- Organism
- Homo sapiens (human)
- Samples
- 142 samples: 108 distinct titles, 31 of them repeatedGroups are read from the sample names, not from the paper. Check the list below.
- Data you can get
- A processed table (series matrix) and supplementary files from NCBI; the raw sequencing reads from ENA. Which of these hold counts depends on the study, so check the file list.
- Paper
- Localized high-risk prostate cancer harbors an androgen receptor activity-low subpopulation susceptible to HER2 inhibitionThe Journal of clinical investigation · 2025
Read the full summary ↓
Direct links to NCBI and ENA, no account and no request form. Pick by what you want to do: take the small processed table to look, the supplementary files to re-analyse, or the original raw data to start over.
Processed table
The series matrix: one table of values per sample as the submitters processed it. The smallest download, and it opens in Excel or R. Start here to see what the data look like.
Supplementary files
The count tables and other files the authors uploaded. Take only the samples you need, or the whole study as GSE152516_RAW.tar (it can run to tens of gigabytes).
Raw sequencing reads
The original FASTQ files, straight from the sequencer, held at ENA. Large, and you align them yourself, so only choose this if you need to re-process the study from scratch.
What the files usually look like: For RNA-seq the counts are usually a table among the supplementary files (look for 'counts', 'expression', 'FPKM' or 'TPM' in the file name). The series matrix of a sequencing study is sometimes nearly empty.
Also filed as BioProject PRJNA639568. Searching any of these in the dataset finder brings you back here.
How we read this: Read from 142 sample titles: 108 distinct titles with little repetition. These groups are guessed from the sample names, not taken from the paper, so check them against the sample list below before relying on them.
- GSM4616823 1001_BX1A-1
- GSM4616824 1001_BX3A-1
- GSM4616825 1001_BX3A-2
- GSM4616826 1001_BX5A-1
- GSM4616827 1001_BX5A-2
- GSM4616828 1001_BX7A-1
- GSM4616829 1001_BX7A-2
- GSM4616830 1002_BX2A-1
- GSM4616831 1002_BX4A-1
- GSM4616832 1002_BX5A-1
- GSM4616833 1003_BX2A-1
- GSM4616834 1003_BX3A-1
- GSM4616835 1003_BX6A-1
- GSM4616836 1004_BX11-1
- GSM4616837 1004_BX7-1
- GSM4616838 1004_BX7-2
- GSM4616839 1004_BX5-1
- GSM4616840 1004_BX5-2
- GSM4616841 1005_BX2A-1
- GSM4616842 1005_BX3A-1
- GSM4616843 1005_BX5A-1
- GSM4616844 1006_BX5A-1
- GSM4616845 1006_BX1A-1
- GSM4616846 1006_BX3A-1
- GSM4616847 1007_BX14A-1
- GSM4616848 1007_BX14A-2
- GSM4616849 1007_BX16A-1
- GSM4616850 1007_BX16A-2
- GSM4616851 1007_BX17A-1
- GSM4616852 1007_BX17A-2
- GSM4616853 1008_BX2A-1
- GSM4616854 1008_BX56A-1
- GSM4616855 1008_BX56A-2
- GSM4616856 1009_BX5A6A-1
- GSM4616857 1009_BX5A6A-2
- GSM4616858 1010_BX2A-1
- GSM4616859 1010_BX3A-1
- GSM4616860 1010_BX4A-1
- GSM4616861 1010_BX4A-2
- GSM4616862 1010_BX4A-3
+ 102 more — browse all 142 samples with per-sample file links →
- GSE328022 Transcriptomic profiling of primary human prostate cancer-associated fibroblasts (CAFs) in response to ADT and Enzalutamide 9 samples shares adt, prostate
- GSE328165 mRNA-based influenza vaccine expands the breadth of the B cell response in humans 109 samples shares adt
- GSE253121 NELF prevents transcriptional readthrough into DNA replication zones in cancer cells 70 samples shares adt
- GSE268308 Transcriptional analysis of metastatic hormone-naïve prostate cancer primary tumour biopsies reveals a relevant role for SOX11 in prostate cancer cell dissemination [Discovery dataset] 78 samples shares prostate
- GSE309004 Molecular determinants of neoadjuvant chemotherapy resistance in breast cancer: An analysis of gene expression and tumor microenvironment 54 samples shares neoadjuvant
- GSE309841 Integrative tissue analysis of men with prostate cancer VIII 42 samples shares prostate
- GSE222196 Treatment of prostate cancer cell lines with Androgen Receptor and Receptor Tyrosine Kinase inhibitors 246 samples shares prostate
- GSE268309 Transcriptional analysis of metastatic hormone-naïve prostate cancer primary tumour biopsies reveals a relevant role for SOX11 in prostate cancer cell dissemination [Validation dataset] 32 samples shares prostate
Metadata from NCBI GEO, cached and refreshed periodically — the NCBI page above is authoritative. Downloads link straight to NCBI/ENA; nothing is proxied through BioTransfer.