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PAXT/NEXT targeting of RNA exosome regulates antisense transcripts through cohesin-mediated long-range contacts [RNA-seq]

GSE154099 Homo sapiens Expression profiling by high throughput sequencing 4 samples Submitted 2025/11/20 Platform GPL16791
Summary
Here, we mapped the binding sites of PAXT/ZFC3H1, NEXT/ZCCHC8 and their shared MTR4 helicase subunit. Our data highlight a key interplay between cohesin-mediated long-range interactions in 3D and ncRNA regulation by MTR4 helicase and nuclear RNA exosome.
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Also filed as BioProject PRJNA645128 and SRA study SRP271106. Searching any of these in the dataset finder brings you back here.

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