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Skin transcriptome of non-communicable inflammatory skin diseases

GSE154200 Homo sapiens (human) RNA-seq (gene expression) 376 samples Submitted 2024/06/20 Platform GPL20301
At a glance

RNA-seq (gene expression) · human · 376 samples

What it is
RNA-seq (gene expression)Gene activity measured by sequencing. The summary does not mention single-cell work, so this is most likely bulk: one average per sample, the usual starting point for comparing groups.
Organism
Homo sapiens (human)
Samples
376 samples
Data you can get
A processed table (series matrix) and supplementary files from NCBI; the raw sequencing reads from ENA. Which of these hold counts depends on the study, so check the file list.
Paper
Characterization of High and Low IFNG-Expressing Subgroups in Atopic DermatitisInternational journal of molecular sciences · 2024
Summary (written by the submitters)
This study includes RNAseq data of lesional and autologous non-lesional skin from patients with non-communicable inflammatory skin diseases, including psoriasis, nummular eczema and atopic dermatitis.
Published in
Characterization of High and Low IFNG-Expressing Subgroups in Atopic Dermatitis
Wasserer S, Jargosch M, Mayer KE et al. · International journal of molecular sciences 2024 · PMID 38892346 · doi:10.3390/ijms25116158
This dataset
Download · which file do I need?

Direct links to NCBI and ENA, no account and no request form. Pick by what you want to do: take the small processed table to look, the supplementary files to re-analyse, or the original raw data to start over.

1 · Just have a look

Processed table

The series matrix: one table of values per sample as the submitters processed it. The smallest download, and it opens in Excel or R. Start here to see what the data look like.

2 · Re-analyse it

Supplementary files

The count tables and other files the authors uploaded. Take only the samples you need, or the whole study as GSE154200_RAW.tar (it can run to tens of gigabytes).

3 · Start from the raw reads

Raw sequencing reads

The original FASTQ files, straight from the sequencer, held at ENA. Large, and you align them yourself, so only choose this if you need to re-process the study from scratch.

What the files usually look like: For RNA-seq the counts are usually a table among the supplementary files (look for 'counts', 'expression', 'FPKM' or 'TPM' in the file name). The series matrix of a sequencing study is sometimes nearly empty.

Also filed as BioProject PRJNA645411 and SRA study SRP272709. Searching any of these in the dataset finder brings you back here.

Study design
A cohort of 376 individual samples

The grouping that defines any comparison lives in the sample characteristics, which GEO records separately from the titles.

How we read this: Sample titles run MUC2676 … MUC7393 and carry no group information.

Samples in this study

+ 336 more — browse all 376 samples with per-sample file links →

Datasets on a similar topic

Search all human RNA-seq datasets in GEO →

Share this dataset

Metadata from NCBI GEO, cached and refreshed periodically — the NCBI page above is authoritative. Downloads link straight to NCBI/ENA; nothing is proxied through BioTransfer.