GEO series
Effect of Mas KO and a novel MAS agonist on pulmonary gene expression
GSE155124
Mus musculus
Expression profiling by high throughput sequencing
12 samples
2025/04/23
GPL13112
Summary
Although both the Mas knockout and the Mas agonist affect roughly the expected types of genes (cytoskeletal, inflammatory, some metabolic), these data imply that (a) the agonist is under some circumstances an antagonist or partial agonist, and that (b) there is a redundant receptor which regulates nearly the same genes, present even with the Mas knockout.
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Paper (PMID 40248213) ↗
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