Pooled CRISPR screening in pancreatic cancer cells implicates co-repressor complexes as a cause of multiple drug resistance via regulation of epithelial-to-mesenchymal transition
Direct links to NCBI, no account and no request form: the whole study as GSE158541_RAW.tar, processed values as the series matrix, the supplementary file directory, and per-sample supplementary files for any of the 39 samples. Raw sequencing reads are also available from ENA.
Also filed as BioProject PRJNA665529 and SRA study SRP279250. Searching any of these in the dataset finder brings you back here.
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+ 39 more — browse all 39 samples with per-sample file links →
- GSE254521 Epigenetic priming promotes acquisition of TKI resistance and oncogene amplification in human lung cancer 146 samples
- GSE301505 Mutual Antagonism Between PRC1 Condensates and SWI/SNF in Chromatin Regulation 210 samples
- GSE254244 Cancer cell type-specific derepression of transposable elements by inhibition of chromatin modifier enzymes 112 samples
- GSE283005 Distinct differentiation trajectories leave lasting impacts on gene regulation and function of V2a neurons 60 samples
- GSE331167 Photoproximity labeling of c-Myc reveals SLK as a cancer-specific co-regulator 47 samples
- GSE287279 Combined SNPs sequencing and allele specific proteomics capture reveal functional causality underpinning the 2p25 prostate cancer susceptibility locus 44 samples
- GSE254366 Epigenome reprogramming through H3K27 and H3K4 trimethylation as a resistance mechanism to DNA methylation inhibition in BRAFV600E-mutated CRC. 36 samples
- GSE210848 Lineage specific chromatin modification guides Pax5 mediated gene expression in neuroendocrine like differentiation of prostate cancer 32 samples
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