BAHD1 links H3K27me3 to gene silencing via a conserved BAH reader module and associated corepressor complex in mammalian cells (RNA-Seq)
RNA-seq (gene expression) · mouse · 12 samples
- What it is
- RNA-seq (gene expression)Gene activity measured by sequencing. The summary does not mention single-cell work, so this is most likely bulk: one average per sample, the usual starting point for comparing groups.
- Organism
- Mus musculus (mouse)
- Samples
- 12 samples: 6 conditions, mostly in duplicateGroups are read from the sample names, not from the paper. Check the list below.
- Data you can get
- A processed table (series matrix) and supplementary files from NCBI; the raw sequencing reads from ENA. Which of these hold counts depends on the study, so check the file list.
- Paper
- A conserved BAH module within mammalian BAHD1 connects H3K27me3 to Polycomb gene silencingNucleic acids research · 2021
Read the full summary ↓
Direct links to NCBI and ENA, no account and no request form. Pick by what you want to do: take the small processed table to look, the supplementary files to re-analyse, or the original raw data to start over.
Processed table
The series matrix: one table of values per sample as the submitters processed it. The smallest download, and it opens in Excel or R. Start here to see what the data look like.
Supplementary files
The count tables and other files the authors uploaded. Take only the samples you need, or the whole study as GSE160057_RAW.tar (it can run to tens of gigabytes).
Raw sequencing reads
The original FASTQ files, straight from the sequencer, held at ENA. Large, and you align them yourself, so only choose this if you need to re-process the study from scratch.
What the files usually look like: For RNA-seq the counts are usually a table among the supplementary files (look for 'counts', 'expression', 'FPKM' or 'TPM' in the file name). The series matrix of a sequencing study is sometimes nearly empty.
Also filed as BioProject PRJNA671707 and SRA study SRP288497. Searching any of these in the dataset finder brings you back here.
Supports a between-group comparison across 12 samples.
How we read this: 6 replicated groups read from 12 sample titles; they account for 12 of them. These groups are guessed from the sample names, not taken from the paper, so check them against the sample list below before relying on them.
- GSM4859355 E14_parent_rep1 E14_parent
- GSM4859356 E14_parent_rep2 E14_parent
- GSM4859357 E14_Bahd1_KO_rep1 E14_Bahd1_KO
- GSM4859358 E14_Bahd1_KO_rep2 E14_Bahd1_KO
- GSM4859359 E14_Bahd1_WT2_res_rep1 E14_Bahd1_WT2_res
- GSM4859360 E14_Bahd1_WT2_res_rep2 E14_Bahd1_WT2_res
- GSM4859361 E14_Bahd1_WT16_res_rep1 E14_Bahd1_WT16_res
- GSM4859362 E14_Bahd1_WT16_res_rep2 E14_Bahd1_WT16_res
- GSM4859363 E14_Bahd1_YA1_res_rep1 E14_Bahd1_YA1_res
- GSM4859364 E14_Bahd1_YA1_res_rep2 E14_Bahd1_YA1_res
- GSM4859365 E14_Bahd1_YA5_res_rep1 E14_Bahd1_YA5_res
- GSM4859366 E14_Bahd1_YA5_res_rep2 E14_Bahd1_YA5_res
- GSE160056 BAHD1 links H3K27me3 to gene silencing via a conserved BAH reader module and associated corepressor complex in mammalian cells (CUT&RUN) 4 samples shares h3k27me3, bahd1, bah, corepressor, silencing, conserved, mammalian, complex
- GSE287033 H3K27me3 and the PRC1-H2AK119ub pathway cooperatively maintain heterochromatin and transcriptional silencing after the loss of H3K9 methylation [RNA-seq] 8 samples shares h3k27me3, silencing
- GSE287032 H3K27me3 and the PRC1-H2AK119ub pathway cooperatively maintain heterochromatin and transcriptional silencing after the loss of H3K9 methylation [ChIP-seq] 20 samples shares h3k27me3, silencing
- GSE293505 Roles of the nuclear receptor corepressor 1 (NCoR1) and the silencing mediator of retinoid and thyroid hormone receptors (SMRT) in the developing brain 20 samples shares corepressor, silencing
- GSE256296 Conserved helical motifs in the Ikaros IDR mediate NuRD corepressor interaction and transcriptional repression [bulk RNAseq] 20 samples shares corepressor, conserved
- GSE256299 Conserved helical motifs in the Ikaros IDR mediate NuRD corepressor interaction and transcriptional repression. 72 samples shares corepressor, conserved
- GSE256297 Conserved helical motifs in the Ikaros IDR mediate NuRD corepressor interaction and transcriptional repression [ChIP-seq] 32 samples shares corepressor, conserved
- GSE256298 Conserved helical motifs in the Ikaros IDR mediate NuRD corepressor interaction and transcriptional repression [Spike-In ChIPseq] 12 samples shares corepressor, conserved
Metadata from NCBI GEO, cached and refreshed periodically — the NCBI page above is authoritative. Downloads link straight to NCBI/ENA; nothing is proxied through BioTransfer.