Transcriptome alteration in wild-type developing oligodendrocytes treated with interferon gamma and thapsigargin in comparison with untreated wild-type developing oligodendrocytes
RNA-seq (gene expression) · mouse · 40 samples
- What it is
- RNA-seq (gene expression)Gene activity measured by sequencing. The summary does not mention single-cell work, so this is most likely bulk: one average per sample, the usual starting point for comparing groups.
- Organism
- Mus musculus (mouse)
- Samples
- 40 samples: 40 samples, each with a distinct title — no replicated groupsGroups are read from the sample names, not from the paper. Check the list below.
- Data you can get
- A processed table (series matrix) and supplementary files from NCBI; the raw sequencing reads from ENA. Which of these hold counts depends on the study, so check the file list.
Direct links to NCBI and ENA, no account and no request form. Pick by what you want to do: take the small processed table to look, the supplementary files to re-analyse, or the original raw data to start over.
Processed table
The series matrix: one table of values per sample as the submitters processed it. The smallest download, and it opens in Excel or R. Start here to see what the data look like.
Supplementary files
The count tables and other files the authors uploaded. Take only the samples you need, or the whole study as GSE161561_RAW.tar (it can run to tens of gigabytes).
Raw sequencing reads
The original FASTQ files, straight from the sequencer, held at ENA. Large, and you align them yourself, so only choose this if you need to re-process the study from scratch.
What the files usually look like: For RNA-seq the counts are usually a table among the supplementary files (look for 'counts', 'expression', 'FPKM' or 'TPM' in the file name). The series matrix of a sequencing study is sometimes nearly empty.
Also filed as BioProject PRJNA678720 and SRA study SRP292746. Searching any of these in the dataset finder brings you back here.
Any grouping that defines a comparison lives in the sample characteristics, which GEO records separately from the titles.
How we read this: Read from 40 sample titles: 40 distinct titles with little repetition. These groups are guessed from the sample names, not taken from the paper, so check them against the sample list below before relying on them.
- GSM4910110 Untreated WT Developing Oligodendrocytes [BP-1]
- GSM4910111 Untreated WT Developing Oligodendrocytes [BP-2]
- GSM4910112 Untreated WT Developing Oligodendrocytes [BP-3]
- GSM4910113 Untreated WT Developing Oligodendrocytes [BP-4]
- GSM4910114 Untreated WT Developing Oligodendrocytes [BP-5]
- GSM4910115 Untreated WT Developing Oligodendrocytes [BP-6]
- GSM4910116 Untreated WT Developing Oligodendrocytes [BP-7]
- GSM4910117 Untreated WT Developing Oligodendrocytes [BP-8]
- GSM4910118 Thapsigargin-treated WT Developing Oligodendrocytes [BP-9]
- GSM4910119 Thapsigargin-treated WT Developing Oligodendrocytes [BP-10]
- GSM4910120 Thapsigargin-treated WT Developing Oligodendrocytes [BP-11]
- GSM4910121 Thapsigargin-treated WT Developing Oligodendrocytes [BP-12]
- GSM4910122 IFN gamma-treated WT Developing Oligodendrocytes [BP-13]
- GSM4910123 IFN gamma-treated WT Developing Oligodendrocytes [BP-14]
- GSM4910124 IFN gamma-treated WT Developing Oligodendrocytes [BP-15]
- GSM4910125 IFN gamma-treated WT Developing Oligodendrocytes [BP-16]
- GSM4910126 IFN gamma-treated WT Developing Oligodendrocytes [BP-17]
- GSM4910127 IFN gamma-treated WT Developing Oligodendrocytes [BP-18]
- GSM4910128 IFN gamma-treated WT Developing Oligodendrocytes [BP-19]
- GSM4910129 IFN gamma-treated WT Developing Oligodendrocytes [BP-20]
- GSM4910130 Untreated WT Developing Oligodendrocytes [BP-21]
- GSM4910131 Untreated WT Developing Oligodendrocytes [BP-22]
- GSM4910132 Untreated WT Developing Oligodendrocytes [BP-23]
- GSM4910133 Untreated WT Developing Oligodendrocytes [BP-24]
- GSM4910134 Untreated WT Developing Oligodendrocytes [BP-25]
- GSM4910135 Untreated WT Developing Oligodendrocytes [BP-26]
- GSM4910136 Untreated WT Developing Oligodendrocytes [BP-27]
- GSM4910137 Untreated WT Developing Oligodendrocytes [BP-28]
- GSM4910138 Thapsigargin-treated WT Developing Oligodendrocytes [BP-29]
- GSM4910139 Thapsigargin-treated WT Developing Oligodendrocytes [BP-30]
- GSM4910140 Thapsigargin-treated WT Developing Oligodendrocytes [BP-31]
- GSM4910141 Thapsigargin-treated WT Developing Oligodendrocytes [BP-32]
- GSM4910142 IFN gamma-treated WT Developing Oligodendrocytes [BP-33]
- GSM4910143 IFN gamma-treated WT Developing Oligodendrocytes [BP-34]
- GSM4910144 IFN gamma-treated WT Developing Oligodendrocytes [BP-35]
- GSM4910145 IFN gamma-treated WT Developing Oligodendrocytes [BP-36]
- GSM4910146 IFN gamma-treated WT Developing Oligodendrocytes [BP-37]
- GSM4910147 IFN gamma-treated WT Developing Oligodendrocytes [BP-38]
- GSM4910148 IFN gamma-treated WT Developing Oligodendrocytes [BP-39]
- GSM4910149 IFN gamma-treated WT Developing Oligodendrocytes [BP-40]
- GSE161562 Transcriptome alteration in Nrf2 mutant developing oligodendrocytes treated with interferon gamma and thapsigargin in comparison with wild-type developing oligodendrocytes treated with interferon gamma and thapsigargin 50 samples shares oligodendrocytes, thapsigargin, alteration, developing, interferon, comparison, wild-type
- GSE287098 Influenza virus-induced type I interferons disrupt alveolar epithelial repair and tight junction integrity in the developing lung 96 samples shares developing, interferon
- GSE235987 Enhancer-AAVs allow genetic access to diverse populations of astrocytes and oligodendrocytes across species 2040 samples shares oligodendrocytes
- GSE104323 Transcriptome analysis of single cells from the developing mouse dentate gyrus 232 samples shares developing
- GSE302188 Multi-omics analysis highlights the link of aging-related cognitive decline with systemic inflammation and alterations of tissue-maintenance 165 samples shares alteration
- GSE276018 Integrated Multi-Omics Analysis Reveals Epigenetic and Sex-Specific Alterations in Colorectal Cancer Cachexia 88 samples shares alteration
- GSE242661 Persistent gene expression and DNA methylation alterations linked to carcinogenic effects of dichloroacetic acid [RNA-seq] 78 samples shares alteration
- GSE240147 Maternal high fat diet induces circadian clock-independent endocrine alterations impacting metabolism of the offspring 70 samples shares alteration
Metadata from NCBI GEO, cached and refreshed periodically — the NCBI page above is authoritative. Downloads link straight to NCBI/ENA; nothing is proxied through BioTransfer.