Transcriptome analysis discloses dysregulated genes in normal appearing tumor-adjacent thyroid tissues from patients with papillary thyroid carcinoma
RNA-seq (gene expression) · human · 74 samples
- What it is
- RNA-seq (gene expression)Gene activity measured by sequencing. The summary does not mention single-cell work, so this is most likely bulk: one average per sample, the usual starting point for comparing groups.
- Organism
- Homo sapiens (human)
- Topic
- Thyroid cancerThis series is part of our curated briefing on it.
- Samples
- 74 samples
- Data you can get
- A processed table (series matrix) and supplementary files from NCBI; the raw sequencing reads from ENA. Which of these hold counts depends on the study, so check the file list.
Read the full summary ↓
Direct links to NCBI and ENA, no account and no request form. Pick by what you want to do: take the small processed table to look, the supplementary files to re-analyse, or the original raw data to start over.
Processed table
The series matrix: one table of values per sample as the submitters processed it. The smallest download, and it opens in Excel or R. Start here to see what the data look like.
Supplementary files
The count tables and other files the authors uploaded. Take only the samples you need, or the whole study as GSE165724_RAW.tar (it can run to tens of gigabytes).
Raw sequencing reads
The original FASTQ files, straight from the sequencer, held at ENA. Large, and you align them yourself, so only choose this if you need to re-process the study from scratch.
What the files usually look like: For RNA-seq the counts are usually a table among the supplementary files (look for 'counts', 'expression', 'FPKM' or 'TPM' in the file name). The series matrix of a sequencing study is sometimes nearly empty.
Also filed as BioProject PRJNA695543 and SRA study SRP303687. Searching any of these in the dataset finder brings you back here.
The sample list for this study is not cached yet. Press Load samples and it will be fetched from NCBI.
+ 74 more — browse all 74 samples with per-sample file links →
- GSE241184 Single cell profiling of primary and paired metastatic lymph node tumors and adjacent normal thyroid in a papillary thyroid carcinoma patient 3 samples same disease briefing · shares papillary, thyroid, normal
- GSE33630 Normal thyrocytes vs papillary vs anaplastic thyroid carcinomas 105 samples same disease briefing · shares papillary, thyroid, normal
- GSE138198 Differentially expression profiling in Hashimoto's thyroiditis (HT), papillary thyroid carcinoma (PTC) with HT in background, PTC without HT in background, micro PTC (mPTC), and three normal thyroid samples (TN). 36 samples same disease briefing · shares papillary, thyroid, normal
- GSE224357 H3K27ac ChIP-seq and RNA-seq of papillary thyroid carcinoma patient's tissues and paired normal tissues 12 samples same disease briefing · shares papillary, thyroid, normal
- GSE212031 Next Generation translatome Sequencing (Ribo-seq) of Papillary Thyroid Carcinoma tissue sample and adjacent normal tissue 8 samples same disease briefing · shares papillary, thyroid, normal
- GSE310793 PRECISE: A prognostic thyroid follicular-cell derived gene signature for papillary thyroid carcinoma 109 samples same disease briefing · shares papillary, thyroid
- GSE275666 Genomic Characterization of Papillary Thyroid Carcinoma: Age Differences in Tumor Aggressiveness and Immune Infiltration 22 samples same disease briefing · shares papillary, thyroid
- GSE285016 FN1 Shapes the Behavior of Papillary Thyroid Carcinoma through Alternative Splicing of EDB Region 10 samples same disease briefing · shares papillary, thyroid
Metadata from NCBI GEO, cached and refreshed periodically — the NCBI page above is authoritative. Downloads link straight to NCBI/ENA; nothing is proxied through BioTransfer.