Small Nucleolar RNAs in the Dlk1-Gtl2 Imprinting Locus Maintains LT-HSC Self-renewal by Regulation of rRNA Modification and Translation
DNA methylation · mouse · 19 samples
- What it is
- DNA methylationChemical marks on DNA that help switch genes on or off.
- Organism
- Mus musculus (mouse)
- Samples
- 19 samples
- Data you can get
- A processed table (series matrix) and supplementary files from NCBI; the raw sequencing reads from ENA. Which of these hold counts depends on the study, so check the file list.
Direct links to NCBI and ENA, no account and no request form. Pick by what you want to do: take the small processed table to look, the supplementary files to re-analyse, or the original raw data to start over.
Processed table
The series matrix: one table of values per sample as the submitters processed it. The smallest download, and it opens in Excel or R. Start here to see what the data look like.
Supplementary files
The count tables and other files the authors uploaded. Take only the samples you need, or the whole study as GSE166518_RAW.tar (it can run to tens of gigabytes).
Raw sequencing reads
The original FASTQ files, straight from the sequencer, held at ENA. Large, and you align them yourself, so only choose this if you need to re-process the study from scratch.
What the files usually look like: Look for beta-value tables or raw IDAT files among the supplementary files.
Also filed as BioProject PRJNA701172 and SRA study SRP305625. Searching any of these in the dataset finder brings you back here.
The sample list for this study is not cached yet. Press Load samples and it will be fetched from NCBI.
+ 19 more — browse all 19 samples with per-sample file links →
- GSE313065 A Polyamine-mediated Posttranslational Modification Required for Macrophage Tissue Residency 47 samples shares modification, translation
- GSE290686 A Polyamine-mediated Posttranslational Modification Required for Macrophage Tissue Residency [RNA-Seq] 24 samples shares modification, translation
- GSE239608 tRNA m1A modification enhances anti-tumor immunity in macrophages by promoting translation of key interferon associated genes 12 samples shares modification, translation
- GSE290459 A Polyamine-mediated Posttranslational Modification Required for Macrophage Tissue Residency [Ribo-seq] 11 samples shares modification, translation
- GSE255253 Effects of the treatment with pegIFNa, Azacytidine or pegIFNa+Azacytidine in LT-HSCs from JAK2-V617F MPN mice or JAK2-V617F;Dnmt3a-KO MPN mice. 31 samples shares lt-hsc
- GSE226803 Transcriptome analysis of bulk-HSCs, LT-HSCs and ST-HSCs. 18 samples shares lt-hsc
- GSE225918 Gene expression profile at single cell level of phenotypic LT-HSCs from single-mutant JAK2 V617F and double mutant JAK2 V617F;Dnmt3a-/- mice 16 samples shares lt-hsc
- GSE198442 Ex vivo cultured mouse LT-HSCs RNA-seq 15 samples shares lt-hsc
Metadata from NCBI GEO, cached and refreshed periodically — the NCBI page above is authoritative. Downloads link straight to NCBI/ENA; nothing is proxied through BioTransfer.