Biphasic effects of pleiotropic cytokine IL-27 during Staphylococcus aureus implant-associated osteomyelitis
RNA-seq (gene expression) · mouse · 24 samples
- What it is
- RNA-seq (gene expression)Gene activity measured by sequencing. The summary does not mention single-cell work, so this is most likely bulk: one average per sample, the usual starting point for comparing groups.
- Organism
- Mus musculus (mouse)
- Samples
- 24 samples
- Data you can get
- A processed table (series matrix) and supplementary files from NCBI; the raw sequencing reads from ENA. Which of these hold counts depends on the study, so check the file list.
Direct links to NCBI and ENA, no account and no request form. Pick by what you want to do: take the small processed table to look, the supplementary files to re-analyse, or the original raw data to start over.
Processed table
The series matrix: one table of values per sample as the submitters processed it. The smallest download, and it opens in Excel or R. Start here to see what the data look like.
Supplementary files
The count tables and other files the authors uploaded. Take only the samples you need, or the whole study as GSE168896_RAW.tar (it can run to tens of gigabytes).
Raw sequencing reads
The original FASTQ files, straight from the sequencer, held at ENA. Large, and you align them yourself, so only choose this if you need to re-process the study from scratch.
What the files usually look like: For RNA-seq the counts are usually a table among the supplementary files (look for 'counts', 'expression', 'FPKM' or 'TPM' in the file name). The series matrix of a sequencing study is sometimes nearly empty.
Also filed as BioProject PRJNA714525 and SRA study SRP310638. Searching any of these in the dataset finder brings you back here.
The sample list for this study is not cached yet. Press Load samples and it will be fetched from NCBI.
+ 24 more — browse all 24 samples with per-sample file links →
- GSE272198 EGFR-MEK1/2 cascade negatively regulates bactericidal function of bone marrow macrophages in mice with Staphylococcus aureus osteomyelitis 6 samples shares staphylococcus, osteomyelitis, aureus
- GSE302226 Mouse kidney Methicillin-resistant Staphylococcus aureus infection time course 28 samples shares staphylococcus, aureus
- GSE286079 Epicutaneous Staphylococcus aureus exposure triggers lung inflammation via epithelia-intrinsic IL-36R signaling in a murine model of the atopic march 25 samples shares staphylococcus, aureus
- GSE320244 Triptolide clears Staphylococcus aureus infection by targeting XIAP to induce host apoptosis while preserving gut microbiota homeostasis [mouse lung macrophages] 18 samples shares staphylococcus, aureus
- GSE252481 Tissue niche influences immune and metabolic profiles to Staphylococcus aureus biofilm 12 samples shares staphylococcus, aureus
- GSE287095 Substance P augments chemokine production by Staphylococcus aureus infected murine osteoclasts 12 samples shares staphylococcus, aureus
- GSE229895 Response of pulmonary mononcytes to Staphylococcus aureus infection 8 samples shares staphylococcus, aureus
- GSE264738 CD4+ T cell-innate immune crosstalk is critical during Staphylococcus aureus biofilm infection. 7 samples shares staphylococcus, aureus
Metadata from NCBI GEO, cached and refreshed periodically — the NCBI page above is authoritative. Downloads link straight to NCBI/ENA; nothing is proxied through BioTransfer.