GEO series
DAXX interacts with histone acylation in gene regulation
GSE169229
Homo sapiens
Expression profiling by high throughput sequencing; Genome binding/occupancy profiling by high throughput sequencing
29 samples
2025/09/06
GPL24676
Summary
Using proteome arrays and mass spectrometry, we find that the histone chaperone DAXX interacts with crotonylated histones. We show that histone crotonylation and gene expression changes promoted by the short-chain fatty acid crotonate depend on DAXX.
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