← BioTransfer GEO Dataset Finder
GEO series

MCF7 cells with LIFR knockdown

GSE174592 Homo sapiens Expression profiling by high throughput sequencing 6 samples Submitted 2024/05/03 Platform GPL18573
Summary
MCF7 cells were infected with lentiviral particles containing LIFR-targeted shRNAs then chemically selected to create a stable pooled population of shLIFR MCF7 cells. The goal of the study was to determine the downstream targets of LIFR in human MCF7 breast cancer cells.
Published in
HDAC inhibitors induce LIFR expression and promote a dormancy phenotype in breast cancer
Clements ME, Holtslander L, Edwards C et al. · Oncogene 2021 · PMID 34247191 · doi:10.1038/s41388-021-01931-1
This dataset
Download

Direct links to NCBI, no account and no request form: the whole study as GSE174592_RAW.tar, processed values as the series matrix, the supplementary file directory, and per-sample supplementary files for any of the 6 samples. Raw sequencing reads are also available from ENA.

Also filed as BioProject PRJNA730596 and SRA study SRP320230. Searching any of these in the dataset finder brings you back here.

Samples in this study

The sample list for this study is not cached yet. Press Sort into groups and it will be fetched from NCBI.

+ 6 more — browse all 6 samples with per-sample file links →

Similar datasets

Search all human RNA-seq datasets in GEO →

Share this dataset

Metadata from NCBI GEO, cached and refreshed periodically — the NCBI page above is authoritative. Downloads link straight to NCBI/ENA; nothing is proxied through BioTransfer.