GEO series

Effect of Lactobacillus plantarum MB452 on the gene expression of the intestinal epithelial cell line Caco-2

GSE18372 Homo sapiens Expression profiling by array 8 samples Submitted 2009/10/07 Platform GPL1708

Summary

The hypothesis of this research was that probiotic bacteria that increase intestinal barrier function achieve this, partly, by increasing the expression of the genes involved in tight junction signalling in healthy intestinal epithelial cells. L. plantarum MB452 isolated from the probiotic product VSL#3 was chosen as the test bacterium because it has a robust, repeatable, positive effect tight junction integrity, as measured by the trans-epithelial electrical resistance (TEER) in vitro.

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Direct links to NCBI, no account and no request form: the whole study as GSE18372_RAW.tar, processed values as the series matrix, the supplementary file directory, and per-sample supplementary files for any of the 8 samples.

Whole study · RAW.tar ↓ Series matrix ↓ All supplementary files ↗

Also filed as BioProject PRJNA118139. Searching any of these in the dataset finder brings you back here.

NCBI GEO page ↗ Paper (PMID 21143932) ↗

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