Air-liquid_interface_Caco-2_culture_with_vasointestinal_peptide_ mimicks_ gut_ mucosal_ barrier_ function_ in_ permeability_ and_bacterial infection
RNA-seq (gene expression) · human · 17 samples
- What it is
- RNA-seq (gene expression)Gene activity measured by sequencing. The summary does not mention single-cell work, so this is most likely bulk: one average per sample, the usual starting point for comparing groups.
- Organism
- Homo sapiens (human)
- Samples
- 17 samples
- Data you can get
- A processed table (series matrix) and supplementary files from NCBI; the raw sequencing reads from ENA. Which of these hold counts depends on the study, so check the file list.
- Paper
- Development of a Caco-2-based intestinal mucosal model to study intestinal barrier properties and bacteria-mucus interactionsGut microbes · 2025
Read the full summary ↓
Direct links to NCBI and ENA, no account and no request form. Pick by what you want to do: take the small processed table to look, the supplementary files to re-analyse, or the original raw data to start over.
Processed table
The series matrix: one table of values per sample as the submitters processed it. The smallest download, and it opens in Excel or R. Start here to see what the data look like.
Supplementary files
The count tables and other files the authors uploaded. Take only the samples you need, or the whole study as GSE283451_RAW.tar (it can run to tens of gigabytes).
Raw sequencing reads
The original FASTQ files, straight from the sequencer, held at ENA. Large, and you align them yourself, so only choose this if you need to re-process the study from scratch.
What the files usually look like: For RNA-seq the counts are usually a table among the supplementary files (look for 'counts', 'expression', 'FPKM' or 'TPM' in the file name). The series matrix of a sequencing study is sometimes nearly empty.
Also filed as BioProject PRJNA1076117 and SRA study SRP489490. Searching any of these in the dataset finder brings you back here.
The sample list for this study is not cached yet. Press Load samples and it will be fetched from NCBI.
+ 17 more — browse all 17 samples with per-sample file links →
- GSE309353 Respiratory syncytial virus nonstructural protein 1 inhibits secretion of cytokines and chemokines by differentiated primary nasal epithelial cells cultured at air-liquid interface 24 samples shares air-liquid, interface, culture
- GSE241292 SARS-CoV-2-infected human nasal epithelial air-liquid interface cultures 16 samples shares air-liquid, interface, culture
- GSE262404 RNA sequencing of bronchial epithelial cells cultured in air-liquid interface for 7 days treated or not with an antibody targeting the sonic hedgehog ligand (AB5E1) 10 samples shares air-liquid, interface, culture
- GSE312700 Transcriptional profile of primary human lung organoid-derived air-liquid interface (ALI) cultures 6 samples shares air-liquid, interface, culture
- GSE316799 Gene expression profile at single cell level of human bronchial epithelium cells cultured at the air-liquid interface (ALI) treated with CdCl2 (10µM) or DMSO (0,1%) 1 samples shares air-liquid, interface, culture
- GSE276369 Comparative Analysis of Caco-2 Cells and Human Jejunal and Duodenal Enteroid-derived Cells in Gel- and Membrane-Based Barrier Models of Intestinal Permeability 13 samples shares caco-2, permeability
- GSE290901 Transcriptomic Analysis of Caco-2 Cells Co-cultured with KERP2-related Entamoeba histolytica Strains 12 samples shares caco-2, culture
- GSE46352 Caco-2 cells cultured in the presence of Lactobacillus fermentum strains AGR1485 or AGR1487 12 samples shares caco-2, culture
Metadata from NCBI GEO, cached and refreshed periodically — the NCBI page above is authoritative. Downloads link straight to NCBI/ENA; nothing is proxied through BioTransfer.