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Transcriptome analysis of immortalized OPLL ligament cells

GSE183752 Homo sapiens Expression profiling by high throughput sequencing 8 samples Submitted 2024/12/31 Platform GPL20795
Summary
Ossification of the posterior longitudinal ligament (OPLL) is formed by heterogeneous ossification of posterior longitudinal ligament. The patho-mechanism of OPLL is still largely unknown. For the rarity of the primary cell samples, here we immortalized the OPLL patient's posterior longitudinal ligament primary cells and normal patient's posterior longitudinal ligament primary cells. The transcriptome of the cells were compared and we found that the osteogenic ability of the OPLL ligament cells were inherited in the immortalized cells.
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Also filed as BioProject PRJNA761977 and SRA study SRP338788. Searching any of these in the dataset finder brings you back here.

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