GEO series
Triptolide sensitizes cancer cells to nucleoside DNA methyltransferase inhibitors through inhibition of DCTPP1 mediated cell-intrinsic resistance [RNA-Seq]
GSE185650
Homo sapiens
Expression profiling by high throughput sequencing
12 samples
2024/10/01
GPL16791
Summary
We show that high DCTPP1 expression was associated with cell-intrinsic resistance to nucleoside DNMT inhibition, and that triptolide and its analogs could overcome this resistance.
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