Depletion of DIS3 from human cell lines
RNA-seq (gene expression) · human · 36 samples
- What it is
- RNA-seq (gene expression)Gene activity measured by sequencing. The summary does not mention single-cell work, so this is most likely bulk: one average per sample, the usual starting point for comparing groups.
- Organism
- Homo sapiens (human)
- Samples
- 36 samples: 8 conditions, mostly in triplicateGroups are read from the sample names, not from the paper. Check the list below.
- Data you can get
- A processed table (series matrix) and supplementary files from NCBI; the raw sequencing reads from ENA. Which of these hold counts depends on the study, so check the file list.
Read the full summary ↓
Direct links to NCBI and ENA, no account and no request form. Pick by what you want to do: take the small processed table to look, the supplementary files to re-analyse, or the original raw data to start over.
Processed table
The series matrix: one table of values per sample as the submitters processed it. The smallest download, and it opens in Excel or R. Start here to see what the data look like.
Supplementary files
The count tables and other files the authors uploaded. Take only the samples you need, or the whole study as GSE188195_RAW.tar (it can run to tens of gigabytes).
Raw sequencing reads
The original FASTQ files, straight from the sequencer, held at ENA. Large, and you align them yourself, so only choose this if you need to re-process the study from scratch.
What the files usually look like: For RNA-seq the counts are usually a table among the supplementary files (look for 'counts', 'expression', 'FPKM' or 'TPM' in the file name). The series matrix of a sequencing study is sometimes nearly empty.
Also filed as BioProject PRJNA777897 and SRA study SRP344578. Searching any of these in the dataset finder brings you back here.
Supports a between-group comparison across 24 samples.
How we read this: 8 replicated groups read from 36 sample titles; they account for 24 of them. These groups are guessed from the sample names, not taken from the paper, so check them against the sample list below before relying on them.
- GSM5671667 cyt_ctrl_1 cyt_ctrl
- GSM5671668 cyt_ctrl_2 cyt_ctrl
- GSM5671669 cyt_ctrl_3 cyt_ctrl
- GSM5671670 cyt_ctrl_A_1 cyt_ctrl_A
- GSM5671671 cyt_ctrl_A_2 cyt_ctrl_A
- GSM5671672 cyt_ctrl_A_3 cyt_ctrl_A
- GSM5671673 cyt_Dis3_1 cyt_Dis3
- GSM5671674 cyt_Dis3_2 cyt_Dis3
- GSM5671675 cyt_Dis3_3 cyt_Dis3
- GSM5671676 cyt_Dis3_A_1 cyt_Dis3_A
- GSM5671677 cyt_Dis3_A_2 cyt_Dis3_A
- GSM5671678 cyt_Dis3_A_3 cyt_Dis3_A
- GSM5671679 chr_ctrl_1 chr_ctrl
- GSM5671680 chr_ctrl_2 chr_ctrl
- GSM5671681 chr_ctrl_3 chr_ctrl
- GSM5671682 chr_ctrl_A_1 chr_ctrl_A
- GSM5671683 chr_ctrl_A_2 chr_ctrl_A
- GSM5671684 chr_ctrl_A_3 chr_ctrl_A
- GSM5671685 chr_Dis3_1 chr_Dis3
- GSM5671686 chr_Dis3_2 chr_Dis3
- GSM5671687 chr_Dis3_3 chr_Dis3
- GSM5671688 chr_Dis3_A_1 chr_Dis3_A
- GSM5671689 chr_Dis3_A_2 chr_Dis3_A
- GSM5671690 chr_Dis3_A_3 chr_Dis3_A
- GSM7438810 cyt_ctrl_1_polyA
- GSM7438811 cyt_ctrl_2_polyA
- GSM7438812 cyt_ctrl_3_polyA
- GSM7438813 cyt_ctrl_A_1_polyA
- GSM7438814 cyt_ctrl_A_2_polyA
- GSM7438815 cyt_ctrl_A_3_polyA
- GSM7438816 cyt_Dis3_1_polyA
- GSM7438817 cyt_Dis3_2_polyA
- GSM7438818 cyt_Dis3_3_polyA
- GSM7438819 cyt_Dis3_A_1_polyA
- GSM7438820 cyt_Dis3_A_2_polyA
- GSM7438821 cyt_Dis3_A_3_polyA
- GSE226482 Single cell RNA sequencing of spinal motor neurons and interneurons differentiated from isogenic FUS and TARDBP human induced pluripotent stem cell lines harbouring ALS-causative mutations 1415 samples shares lines
- GSE288929 Baseline Gene Expression in Human Derived Cell Lines 180 samples shares lines
- GSE336490 Comparative toxicogenomic profiling of human epithelial cell lines exposed to hazardous chemicals 120 samples shares lines
- GSE216561 Depletion-assisted multiplexing cell-free RNA sequencing reveals distinct human and microbial signatures in plasma versus extracellular vesicle 113 samples shares depletion
- GSE222196 Treatment of prostate cancer cell lines with Androgen Receptor and Receptor Tyrosine Kinase inhibitors 246 samples shares lines
- GSE288221 RNA sequencing human melanoma, glioblastoma and pancreatic adenocarcinoma cell lines 32 samples shares lines
- GSE336141 Systematic transcriptomic comparison of the time-serial interferon responses in two widely used human cell lines 30 samples shares lines
- GSE250236 Heterogeneous expression of cell surface markers in human myeloma cell lines: implications for disease modelling and therapeutic targeting 18 samples shares lines
Metadata from NCBI GEO, cached and refreshed periodically — the NCBI page above is authoritative. Downloads link straight to NCBI/ENA; nothing is proxied through BioTransfer.