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Systematic transcriptomic comparison of the time-serial interferon responses in two widely used human cell lines

GSE336141 Homo sapiens Expression profiling by high throughput sequencing 30 samples 2026/07/20 GPL29480
Summary
Here, we systematically compared the transcriptomic dynamics of IFN‑γ stimulation in HEK293T and HeLa cells across a time series (0–24 h) in duplicate. Our analysis uncovered both shared and cell‑type‑specific transcriptional responses, providing insights into the temporal regulation of interferon signaling in distinct human epithelial backgrounds.
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