Epithelial deletion of CUL4B increased myeloid-derived suppressor cells-mediated immunosuppression to promote ApcMin/+ tumor formation
RNA-seq (gene expression) · mouse · 12 samples
- What it is
- RNA-seq (gene expression)Gene activity measured by sequencing. The summary does not mention single-cell work, so this is most likely bulk: one average per sample, the usual starting point for comparing groups.
- Organism
- Mus musculus (mouse)
- Samples
- 12 samples
- Data you can get
- A processed table (series matrix) and supplementary files from NCBI; the raw sequencing reads from ENA. Which of these hold counts depends on the study, so check the file list.
Read the full summary ↓
Direct links to NCBI and ENA, no account and no request form. Pick by what you want to do: take the small processed table to look, the supplementary files to re-analyse, or the original raw data to start over.
Processed table
The series matrix: one table of values per sample as the submitters processed it. The smallest download, and it opens in Excel or R. Start here to see what the data look like.
Supplementary files
The count tables and other files the authors uploaded. Take only the samples you need, or the whole study as GSE189382_RAW.tar (it can run to tens of gigabytes).
Raw sequencing reads
The original FASTQ files, straight from the sequencer, held at ENA. Large, and you align them yourself, so only choose this if you need to re-process the study from scratch.
What the files usually look like: For RNA-seq the counts are usually a table among the supplementary files (look for 'counts', 'expression', 'FPKM' or 'TPM' in the file name). The series matrix of a sequencing study is sometimes nearly empty.
Also filed as BioProject PRJNA782872 and SRA study SRP347409. Searching any of these in the dataset finder brings you back here.
The sample list for this study is not cached yet. Press Load samples and it will be fetched from NCBI.
+ 12 more — browse all 12 samples with per-sample file links →
- GSE222940 CUL4B functions as a tumor suppressor in KRAS-driven lung tumor by inhibiting recruitment of myeloid-derived suppressor cells 4 samples shares cul4b, myeloid-derived, suppressor
- GSE311155 Age- and Sex- Driven Transcriptional and Metabolic Diversity in Myeloid-Derived Suppressor Cells After Mouse Sepsis 57 samples shares myeloid-derived, suppressor
- GSE223029 Increase of blood CSF3R+ myeloid-derived suppressor cell predicts breast cancer recurrence 24 samples shares myeloid-derived, suppressor
- GSE305141 BM-MSC-Derived Migrasomes Reverse Stroke-Induced Thymic Atrophy and Immunosuppression via Pin1 Delivery to Thymic Epithelial Cells 15 samples shares immunosuppression, epithelial
- GSE265871 Methylation of SRSF2P95H by SETD2 suppresses myeloid-derived suppressor cell function by inhibiting inflammatory signaling in myelodysplastic syndrome 13 samples shares myeloid-derived, suppressor
- GSE295742 Mitochondrial transfer to granulocytic myeloid-derived suppressor cells augments immunosuppressive activity 12 samples shares myeloid-derived, suppressor
- GSE252129 Age-related Increase of CD38 Directs Osteoclastogenic Potential of Monocytic Myeloid-Derived Suppressor Cells through Mitochondrial Dysfunction 12 samples shares myeloid-derived, suppressor
- GSE306006 Nanoparticle-boosted myeloid-derived suppressor cell therapy for immune reprogramming in multiple sclerosis 12 samples shares myeloid-derived, suppressor
Metadata from NCBI GEO, cached and refreshed periodically — the NCBI page above is authoritative. Downloads link straight to NCBI/ENA; nothing is proxied through BioTransfer.