Transcriptomic analysis of placenta and its released extracellular vesicles in normal and preeclampsia pregnancies: insigths into novel biomarkers and mechanisms of disease
RNA-seq (gene expression) · human · 41 samples
- What it is
- RNA-seq (gene expression)Gene activity measured by sequencing. The summary does not mention single-cell work, so this is most likely bulk: one average per sample, the usual starting point for comparing groups.
- Organism
- Homo sapiens (human)
- Samples
- 41 samples
- Data you can get
- A processed table (series matrix) and supplementary files from NCBI; the raw sequencing reads from ENA. Which of these hold counts depends on the study, so check the file list.
Read the full summary ↓
Direct links to NCBI and ENA, no account and no request form. Pick by what you want to do: take the small processed table to look, the supplementary files to re-analyse, or the original raw data to start over.
Processed table
The series matrix: one table of values per sample as the submitters processed it. The smallest download, and it opens in Excel or R. Start here to see what the data look like.
Supplementary files
The count tables and other files the authors uploaded. Take only the samples you need, or the whole study as GSE190971_RAW.tar (it can run to tens of gigabytes).
Raw sequencing reads
The original FASTQ files, straight from the sequencer, held at ENA. Large, and you align them yourself, so only choose this if you need to re-process the study from scratch.
What the files usually look like: For RNA-seq the counts are usually a table among the supplementary files (look for 'counts', 'expression', 'FPKM' or 'TPM' in the file name). The series matrix of a sequencing study is sometimes nearly empty.
Also filed as BioProject PRJNA789228 and SRA study SRP350887. Searching any of these in the dataset finder brings you back here.
The sample list for this study is not cached yet. Press Load samples and it will be fetched from NCBI.
+ 41 more — browse all 41 samples with per-sample file links →
- GSE268230 Extracellular vesicles alter trophoblast function in pregnancies complicated by COVID-19 129 samples shares extracellular, pregnancies, vesicles
- GSE294455 Sphingolipids in extracellular vesicles released from the skeletal muscle plasma membrane control muscle stem cell fate during muscle regeneration 10 samples shares extracellular, released, vesicles
- GSE255775 Transcriptomic Profiling of Plasma Extracellular Vesicles Enables Reliable Annotation of the Cancer-specific Transcriptome and Molecular Subtype 319 samples shares extracellular, vesicles
- GSE297395 Extracellular vesicles and their RNA cargo facilitate bidirectional cross-kingdom communication between human and bacterial cells [RNA-Seq] 105 samples shares extracellular, vesicles
- GSE242856 The RNA content of plasma-derived extracellular vesicles in cerebral malaria 84 samples shares extracellular, vesicles
- GSE302211 Extracellular Vesicle Online Knowledge Explorer (EVOKE) - A guiding tool for the selection of methods to prepare extracellular vesicles from human biofluids II 73 samples shares extracellular, vesicles
- GSE306864 Placental transcriptome profiles in late-onset preeclampsia: a cross-sectional observational analysis stratified by fetal sex 58 samples shares preeclampsia, placenta
- GSE272342 Transcriptomics profiling of singleton and twin placentas in the absence or presence of preeclampsia. 45 samples shares preeclampsia, placenta
Metadata from NCBI GEO, cached and refreshed periodically — the NCBI page above is authoritative. Downloads link straight to NCBI/ENA; nothing is proxied through BioTransfer.