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Illumina GoldenGate Methylation array data for X-CGD patients and healthy controls

GSE19515 Homo sapiens Methylation profiling by array 27 samples Submitted 2009/12/17 Platform GPL9183
Summary
We report on the molecular and cellular events observed in two patients treated by gene therapy in 2004. After the initial resolution of bacterial and fungal infections, both patients exhibited silencing of transgene expression due to methylation of the viral promoter, and myelodysplasia with monosomy 7 as a result of insertional activation of EVI1. In line with this observation, a genome wide methylation analysis of 807 cancer related genes revealed a DNA methylation pattern characteristic of MDS and AML patients.
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Direct links to NCBI, no account and no request form: the whole study as GSE19515_RAW.tar, processed values as the series matrix, the supplementary file directory, and per-sample supplementary files for any of the 27 samples.

Also filed as BioProject PRJNA122339. Searching any of these in the dataset finder brings you back here.

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