Global gene expression profile of cortices from Aifm1 KI and Hq mutant and control mouse
RNA-seq (gene expression) · mouse · 16 samples
- What it is
- RNA-seq (gene expression)Gene activity measured by sequencing. The summary does not mention single-cell work, so this is most likely bulk: one average per sample, the usual starting point for comparing groups.
- Organism
- Mus musculus (mouse)
- Samples
- 16 samples: 4 × Aifm1-KI vs 4 × Aifm1-WT vs 4 × Hq-mut vs 4 × Hq-WTGroups are read from the sample names, not from the paper. Check the list below.
- Data you can get
- A processed table (series matrix) and supplementary files from NCBI; the raw sequencing reads from ENA. Which of these hold counts depends on the study, so check the file list.
- Paper
- Integrated analysis of transcriptomic and proteomic alterations in mouse models of ALS/FTD identify early metabolic adaptions with similarities to mitochondrial dysfunction disordersAmyotrophic lateral sclerosis & frontotemporal degeneration · 2024
Direct links to NCBI and ENA, no account and no request form. Pick by what you want to do: take the small processed table to look, the supplementary files to re-analyse, or the original raw data to start over.
Processed table
The series matrix: one table of values per sample as the submitters processed it. The smallest download, and it opens in Excel or R. Start here to see what the data look like.
Supplementary files
The count tables and other files the authors uploaded. Take only the samples you need, or the whole study as GSE196414_RAW.tar (it can run to tens of gigabytes).
Raw sequencing reads
The original FASTQ files, straight from the sequencer, held at ENA. Large, and you align them yourself, so only choose this if you need to re-process the study from scratch.
What the files usually look like: For RNA-seq the counts are usually a table among the supplementary files (look for 'counts', 'expression', 'FPKM' or 'TPM' in the file name). The series matrix of a sequencing study is sometimes nearly empty.
Also filed as BioProject PRJNA804867 and SRA study SRP359056. Searching any of these in the dataset finder brings you back here.
Supports a between-group comparison across 16 samples.
How we read this: 4 replicated groups read from 16 sample titles; they account for 16 of them. These groups are guessed from the sample names, not taken from the paper, so check them against the sample list below before relying on them.
- GSM5880593 Aifm1-KI Rep1 Aifm1-KI
- GSM5880594 Aifm1-KI Rep2 Aifm1-KI
- GSM5880595 Aifm1-KI Rep3 Aifm1-KI
- GSM5880596 Aifm1-KI Rep4 Aifm1-KI
- GSM5880597 Aifm1-WT Rep1 Aifm1-WT
- GSM5880598 Aifm1-WT Rep2 Aifm1-WT
- GSM5880599 Aifm1-WT Rep3 Aifm1-WT
- GSM5880600 Aifm1-WT Rep4 Aifm1-WT
- GSM5880601 Hq-mut Rep1 Hq-mut
- GSM5880602 Hq-mut Rep2 Hq-mut
- GSM5880603 Hq-mut Rep3 Hq-mut
- GSM5880604 Hq-mut Rep4 Hq-mut
- GSM5880605 Hq-WT Rep1 Hq-WT
- GSM5880606 Hq-WT Rep2 Hq-WT
- GSM5880607 Hq-WT Rep3 Hq-WT
- GSM5880608 Hq-WT Rep4 Hq-WT
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- GSE267388 mRNA expression profiles in hearts from sepsis-induced myocardial dysfunction mouse modles and controls 10 samples shares control
- GSE242709 Global transcriptional profiles of primary and secondary cellular senescence in vivo by oncogene-induced senescence (OIS) and stress-induced senescence (SIS) 76 samples shares global
- GSE283201 Comparative gene expression profiling analysis of hippocampus and liver RNA-seq data for young (3-month-old) and aged (22-month-old) WT mice in both control and ethanol feeding conditions. 32 samples shares control
- GSE269191 ZEB2 is a Master Switch Controlling the Tumor-Associated Macrophage Program [in vivo] 145 samples shares control
- GSE133897 Transcriptomic and proteomic multi-model global gene expression analysis reveals regulatory signatures during ischemia stroke (photothrombotic cerebral ischemia stroke) 18 samples shares global
- GSE310620 RNA-seq in aortic smooth muscle cells from a mice lacking Arg1 expression in erytrhrocytes (RBC.ARG1-KO) and their litter mate controls (RBC.ARG1-WT) after culture in standard DMEM or foam cell medium (DIAM) 16 samples shares control
- GSE274992 Splenic fibroblasts control marginal zone B-cell movement and function via two distinct Notch2-dependent regulatory programs 119 samples shares control
Metadata from NCBI GEO, cached and refreshed periodically — the NCBI page above is authoritative. Downloads link straight to NCBI/ENA; nothing is proxied through BioTransfer.