GEO series
Phf6 mutation induces leukemogenesis through altered chromatin state in mice (ChIP-Seq)
GSE198500
Mus musculus
Genome binding/occupancy profiling by high throughput sequencing
12 samples
2026/06/01
GPL19057
Summary
To investigate the effect of PHF6 mutations in leukemogenesis, we generated Phf6R274X transgenetic(Tg) mice. Then we purified the cKit+ cells from bone marrow of Phf6R274XTg and WT mice, and performed ChIP-seq to study histone modification in hematopoietic stem and progenitor cells.
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