RNA sequencing of normal and unilateral ureteral obstruction (UUO) operated mouse kidneys
RNA-seq (gene expression) · mouse · 10 samples
- What it is
- RNA-seq (gene expression)Gene activity measured by sequencing. The summary does not mention single-cell work, so this is most likely bulk: one average per sample, the usual starting point for comparing groups.
- Organism
- Mus musculus (mouse)
- Samples
- 10 samples: 10 samples, each with a distinct title — no replicated groupsGroups are read from the sample names, not from the paper. Check the list below.
- Data you can get
- A processed table (series matrix) and supplementary files from NCBI; the raw sequencing reads from ENA. Which of these hold counts depends on the study, so check the file list.
- Paper
- Single cell G-protein coupled receptor profiling of activated kidney fibroblasts expressing transcription factor 21British journal of pharmacology · 2023
Direct links to NCBI and ENA, no account and no request form. Pick by what you want to do: take the small processed table to look, the supplementary files to re-analyse, or the original raw data to start over.
Processed table
The series matrix: one table of values per sample as the submitters processed it. The smallest download, and it opens in Excel or R. Start here to see what the data look like.
Supplementary files
The count tables and other files the authors uploaded. Take only the samples you need, or the whole study as GSE198962_RAW.tar (it can run to tens of gigabytes).
Raw sequencing reads
The original FASTQ files, straight from the sequencer, held at ENA. Large, and you align them yourself, so only choose this if you need to re-process the study from scratch.
What the files usually look like: For RNA-seq the counts are usually a table among the supplementary files (look for 'counts', 'expression', 'FPKM' or 'TPM' in the file name). The series matrix of a sequencing study is sometimes nearly empty.
Also filed as BioProject PRJNA817581 and SRA study SRP364848. Searching any of these in the dataset finder brings you back here.
Any grouping that defines a comparison lives in the sample characteristics, which GEO records separately from the titles.
How we read this: Read from 10 sample titles: 10 distinct titles with little repetition. These groups are guessed from the sample names, not taken from the paper, so check them against the sample list below before relying on them.
- GSM5961740 Sham-1 [S16]
- GSM5961741 Sham-2 [S17]
- GSM5961742 Sham-3 [S18]
- GSM5961743 Sham-4 [S19]
- GSM5961744 Sham-5 [S20]
- GSM5961745 UUO-1 [S6]
- GSM5961746 UUO-2 [S7]
- GSM5961747 UUO-3 [S8]
- GSM5961748 UUO-4 [S9]
- GSM5961749 UUO-5 [S10]
- GSE299417 RNA sequencing of kidneys of sham-operated mice and mice with unilateral ureteral obstruction (UUO) treated with istradefylline or vehicle 24 samples shares uuo, obstruction, unilateral, ureteral, operated, kidneys
- GSE198829 RNA sequencing analysis of mouse kidney fibroblasts isolated from control kidneys or UUO surgery operated kidneys 11 samples shares uuo, operated, kidneys
- GSE264184 Kidney single cell sequencing results from 10-day unilateral ureteral obstruction mice 2 samples shares obstruction, unilateral, ureteral
- GSE271305 RNA-sequncing in UUO-induced PTC-specific p300 knockout mouse kidneys 9 samples shares uuo, kidneys
- GSE297022 U3 - acute UUO kidneys 1 samples shares uuo, kidneys
- GSE175412 Single-cell RNA sequencing of adult mouse fibrotic kidney induced by unilateral uretral obstruction 3 samples shares obstruction, unilateral
- GSE36496 Murine Kidney Tissue: Unilateral ureteral obstructed mice vs. Sham control 22 samples shares unilateral, ureteral
- GSE306281 RNA-seq of kidney transcriptome following UUO injury 75 samples shares uuo
Metadata from NCBI GEO, cached and refreshed periodically — the NCBI page above is authoritative. Downloads link straight to NCBI/ENA; nothing is proxied through BioTransfer.