RNA-seq of kidney transcriptome following UUO injury
RNA-seq (gene expression) · mouse · 75 samples
- What it is
- RNA-seq (gene expression)Gene activity measured by sequencing. The summary does not mention single-cell work, so this is most likely bulk: one average per sample, the usual starting point for comparing groups.
- Organism
- Mus musculus (mouse)
- Samples
- 75 samples: 11 conditions, mostly with about 7 replicates eachGroups are read from the sample names, not from the paper. Check the list below.
- Data you can get
- A processed table (series matrix) and supplementary files from NCBI; the raw sequencing reads from ENA. Which of these hold counts depends on the study, so check the file list.
- Paper
- TIE2 activation by antibody-clustered endogenous angiopoietin-2 prevents capillary loss and fibrosis in experimental kidney diseaseThe Journal of clinical investigation · 2025
Read the full summary ↓
Direct links to NCBI and ENA, no account and no request form. Pick by what you want to do: take the small processed table to look, the supplementary files to re-analyse, or the original raw data to start over.
Processed table
The series matrix: one table of values per sample as the submitters processed it. The smallest download, and it opens in Excel or R. Start here to see what the data look like.
Supplementary files
The count tables and other files the authors uploaded. Take only the samples you need, or the whole study as GSE306281_RAW.tar (it can run to tens of gigabytes).
Raw sequencing reads
The original FASTQ files, straight from the sequencer, held at ENA. Large, and you align them yourself, so only choose this if you need to re-process the study from scratch.
What the files usually look like: For RNA-seq the counts are usually a table among the supplementary files (look for 'counts', 'expression', 'FPKM' or 'TPM' in the file name). The series matrix of a sequencing study is sometimes nearly empty.
Also filed as BioProject PRJNA1310405 and SRA study SRP612581. Searching any of these in the dataset finder brings you back here.
Supports a between-group comparison across 75 samples.
How we read this: 11 replicated groups read from 75 sample titles; they account for 75 of them. These groups are guessed from the sample names, not taken from the paper, so check them against the sample list below before relying on them.
- GSM9196715 B4 B
- GSM9196716 A6 A
- GSM9196717 B6 B
- GSM9196718 B7 B
- GSM9196719 P_1 P
- GSM9196720 P_2 P
- GSM9196721 P_3 P
- GSM9196722 P_4 P
- GSM9196723 E3 E
- GSM9196724 F5 F
- GSM9196725 E6 E
- GSM9196726 F6 F
- GSM9196727 N_9 N
- GSM9196728 N_11 N
- GSM9196729 N_12 N
- GSM9196730 C6 C
- GSM9196731 D6 D
- GSM9196732 H6 H
- GSM9196733 D7 D
- GSM9196734 P_5 P
- GSM9196735 P_6 P
- GSM9196736 P_7 P
- GSM9196737 P_8 P
- GSM9196738 G5 G
- GSM9196739 H5 H
- GSM9196740 G6 G
- GSM9196741 C7 C
- GSM9196742 O_9 O
- GSM9196743 O_11 O
- GSM9196744 O_12 O
- GSM9196745 F3 F
- GSM9196746 A8 A
- GSM9196747 F9 F
- GSM9196748 G_5 G
- GSM9196749 G_6 G
- GSM9196750 G_7 G
- GSM9196751 G_8 G
- GSM9196752 E7 E
- GSM9196753 B8 B
- GSM9196754 G_1 G
+ 35 more — browse all 75 samples with per-sample file links →
- GSE326452 Bulk RNA-seq of mouse brain following closed head injury: role of IL-1R1 signaling 200 samples shares following, rna-seq, injury
- GSE277487 Single-nucleus RNA-seq of mouse cortex following CCI-induced traumatic brain injury across multiple time points 12 samples shares following, rna-seq, injury
- GSE198962 RNA sequencing of normal and unilateral ureteral obstruction (UUO) operated mouse kidneys 10 samples shares uuo, kidney
- GSE239287 Single-cell transcriptome sequencing of macrophages in acute kidney injury(AKI) to chronic kidney dieases(CKD) 17 samples shares kidney, injury
- GSE276682 Single-cell transcriptome analysis revealed cellular reprogramming following Tetramethylpyrazine treatment in LPS-induced acute lung injury 12 samples shares following, injury
- GSE267650 Mouse kidney ischemia-reperfusion injury time course 57 samples shares kidney, injury
- GSE228960 Bulk RNA-Seq from kidneys of uninephrectomized db/db mice as a model of severe diabetic kidney disease 28 samples shares rna-seq, kidney
- GSE173999 Single-cel RNA-seq of Mouse Olfactory Epithelium for Understanding Age-associated Neuronal Injury Response 19 samples shares rna-seq, injury
Metadata from NCBI GEO, cached and refreshed periodically — the NCBI page above is authoritative. Downloads link straight to NCBI/ENA; nothing is proxied through BioTransfer.