CK2 phosphorylation of cap methyltransferase CMTR1 promotes RNAPII interaction
RNA-seq (gene expression) · mouse · 12 samples
- What it is
- RNA-seq (gene expression)Gene activity measured by sequencing. The summary does not mention single-cell work, so this is most likely bulk: one average per sample, the usual starting point for comparing groups.
- Organism
- Mus musculus (mouse)
- Samples
- 12 samples: 4 × 15A_Cre vs 4 × EV_Cre vs 4 × WT_CreGroups are read from the sample names, not from the paper. Check the list below.
- Data you can get
- A processed table (series matrix) and supplementary files from NCBI; the raw sequencing reads from ENA. Which of these hold counts depends on the study, so check the file list.
- Paper
- CK2 phosphorylation of CMTR1 promotes RNA cap formation and influenza virus infectionCell reports · 2024
Direct links to NCBI and ENA, no account and no request form. Pick by what you want to do: take the small processed table to look, the supplementary files to re-analyse, or the original raw data to start over.
Processed table
The series matrix: one table of values per sample as the submitters processed it. The smallest download, and it opens in Excel or R. Start here to see what the data look like.
Supplementary files
The count tables and other files the authors uploaded. Take only the samples you need, or the whole study as GSE200103_RAW.tar (it can run to tens of gigabytes).
Raw sequencing reads
The original FASTQ files, straight from the sequencer, held at ENA. Large, and you align them yourself, so only choose this if you need to re-process the study from scratch.
What the files usually look like: For RNA-seq the counts are usually a table among the supplementary files (look for 'counts', 'expression', 'FPKM' or 'TPM' in the file name). The series matrix of a sequencing study is sometimes nearly empty.
Also filed as BioProject PRJNA823002 and SRA study SRP367421. Searching any of these in the dataset finder brings you back here.
Supports a between-group comparison across 12 samples.
How we read this: 3 replicated groups read from 12 sample titles; they account for 12 of them. These groups are guessed from the sample names, not taken from the paper, so check them against the sample list below before relying on them.
- GSM6008727 15A_Cre_1 15A_Cre
- GSM6008728 15A_Cre_2 15A_Cre
- GSM6008729 15A_Cre_3 15A_Cre
- GSM6008730 15A_Cre_4 15A_Cre
- GSM6008735 EV_Cre_1 EV_Cre
- GSM6008736 EV_Cre_2 EV_Cre
- GSM6008737 EV_Cre_3 EV_Cre
- GSM6008738 EV_Cre_4 EV_Cre
- GSM6008739 WT_Cre_1 WT_Cre
- GSM6008740 WT_Cre_2 WT_Cre
- GSM6008741 WT_Cre_3 WT_Cre
- GSM6008742 WT_Cre_4 WT_Cre
- GSE309176 CK2-mediated DEK Phosphorylation Drives PBX3 Overexpression: A Core Event in Hematopoietic Stem Cell-to-Leukemia Stem Cell Transformation [RNA-seq] 8 samples shares ck2, phosphorylation
- GSE313425 Genetic and pharmaceutical manipulation of H3K9 methyltransferase Suv39h1 promotes liver regeneration by unleashing HMGB2 transcription [1] 8 samples shares methyltransferase, promotes
- GSE313198 Genetic and pharmaceutical manipulation of H3K9 methyltransferase Suv39h1 promotes liver regeneration by unleashing HMGB2 transcription [2] 8 samples shares methyltransferase, promotes
- GSE277545 The methyltransferase MLL4 promotes non-alcoholic steatohepatitis by enhancing NF-κB signaling 7 samples shares methyltransferase, promotes
- GSE298142 The m6A methyltransferase METTL14 promotes oncogenic Kras induced juvenile myelomonocytic leukemia through dysregulating autophagy [RNA-seq] 3 samples shares methyltransferase, promotes
- GSE298134 The m6A methyltransferase METTL14 promotes oncogenic Kras induced juvenile myelomonocytic leukemia through dysregulating autophagy 12 samples shares methyltransferase, promotes
- GSE313427 Genetic and pharmaceutical manipulation of H3K9 methyltransferase Suv39h1 promotes liver regeneration by unleashing HMGB2 transcription 2 samples shares methyltransferase, promotes
- GSE296499 CK2α deletion in the hematopoietic compartment leads to mild alterations in terminally differentiated cells and expansion of stem cells 22 samples shares ck2
Metadata from NCBI GEO, cached and refreshed periodically — the NCBI page above is authoritative. Downloads link straight to NCBI/ENA; nothing is proxied through BioTransfer.