Single cell transcriptomic analysis of human retina
Single-cell RNA-seq · human · 33 samples
- What it is
- Single-cell RNA-seqGene activity measured in thousands of individual cells, so cell types can be told apart.
- Organism
- Homo sapiens (human)
- Samples
- 33 samples: 33 samples, each with a distinct title — no replicated groupsGroups are read from the sample names, not from the paper. Check the list below.
- Data you can get
- A processed table (series matrix) and supplementary files from NCBI; the raw sequencing reads from ENA. Which of these hold counts depends on the study, so check the file list.
Direct links to NCBI and ENA, no account and no request form. Pick by what you want to do: take the small processed table to look, the supplementary files to re-analyse, or the original raw data to start over.
Processed table
The series matrix: one table of values per sample as the submitters processed it. The smallest download, and it opens in Excel or R. Start here to see what the data look like.
Supplementary files
The count tables and other files the authors uploaded. Take only the samples you need, or the whole study as GSE202146_RAW.tar (it can run to tens of gigabytes).
Raw sequencing reads
The original FASTQ files, straight from the sequencer, held at ENA. Large, and you align them yourself, so only choose this if you need to re-process the study from scratch.
What the files usually look like: Single-cell studies usually ship their counts as 10x files (matrix.mtx, barcodes.tsv, features.tsv), an .h5 file, or an .rds / .h5ad object that Seurat or Scanpy can open. Look for those among the supplementary files.
Also filed as BioProject PRJNA834793 and SRA study SRP373452. Searching any of these in the dataset finder brings you back here.
Any grouping that defines a comparison lives in the sample characteristics, which GEO records separately from the titles.
How we read this: Read from 33 sample titles: 33 distinct titles with little repetition. These groups are guessed from the sample names, not taken from the paper, so check them against the sample list below before relying on them.
- GSM6098551 M030192_1 Macula Choroid
- GSM6098552 M030192_1 Macula Retina
- GSM6098553 M030192_1 Peripheral Choroid
- GSM6098554 M030192_1 Peripheral Retina
- GSM6098555 M030192_2 Macula Retina
- GSM6098556 M030192_2 Peripheral Retina
- GSM6098557 M030192_3 Macula Choroid
- GSM6098558 M030192_3 Macula Retina
- GSM6098559 M030192_3 Peripheral Choroid
- GSM6098560 M030192_3 Peripheral Retina
- GSM6098561 M030192_4 Macula Choroid
- GSM6098562 M030192_4 Macula Retina
- GSM6098563 M030192_4 Peripheral Choroid
- GSM6098564 M030192_4 Peripheral Retina
- GSM6098565 M030192_5 Hashing
- GSM6098566 M030192_6 Macula Retina
- GSM6098567 M030192_6 Peripheral Retina
- GSM6098568 M030192_7 Macula Retina
- GSM6098569 M030192_7 Peripheral Retina
- GSM6098570 M030192_8 Macula Choroid
- GSM6098571 M030192_8 Macula Retina
- GSM6098572 M030192_8 Peripheral Choroid
- GSM6098573 M030192_8 Peripheral Retina
- GSM6098574 M030192_9 Macula Retina
- GSM6098575 M030192_9 Peripheral Retina
- GSM6098576 M030192_10 Macula Choroid
- GSM6098577 M030192_10 Macula Retina
- GSM6098578 M030192_10 Peripheral Choroid
- GSM6098579 M030192_10 Peripheral Retina
- GSM6098580 M030192_11 Macula Retina
- GSM6098581 M030192_11 Peripheral Retina
- GSM6098582 M030192_12 Macula Retina
- GSM6098583 M030192_12 Peripheral Retina
- GSE242184 In vitro pigmentation of human iPSC-derived retinal pigment epithelium cells is not indicative of their quality for cell transplantation 4022 samples shares retina
- GSE270418 Unraveling the web of nAMD: A transcriptomic analysis of age-related macular degeneration-associated cytokines in primary human retinal endothelial cells. 48 samples shares retina
- GSE135922 Single-cell transcriptomics of the human retinal pigment epithelium and choroid in health and macular degeneration 14 samples shares retina
- GSE285393 Single-Cell Transcriptomic Profiling of Xenotransplanted Retinal Organoids Derived from the WA09 CRX-tdTomato Human Embryonic Stem Cell Line 6 samples shares retina
- GSE328981 Quantum Molecular Resonance attenuates an oxidative stress-induced chimeric transcriptome program in human retinal pigment epithelial cells, preserving RNA structural fidelity 108 samples shares retina
- GSE115828 Integrated analysis of genetic variants regulating retinal transcriptome (GREx) identifies genes underlying age-related macular degeneration 523 samples shares retina
- GSE339345 Transcriptomic analysis of PM2.5 and/or fucoidan-treated ARPE-19 retinal pigment epithelial cells 8 samples shares retina
- GSE337805 Single-cell analysis reveals impaired Müller glia-mediated intercellular communication and photoreceptor pathology in USH1C retinal organoids 7 samples shares retina
Metadata from NCBI GEO, cached and refreshed periodically — the NCBI page above is authoritative. Downloads link straight to NCBI/ENA; nothing is proxied through BioTransfer.