m6a methylation drives IMP1 regulation during human neuronal differentiation [RNA-seq]
DNA methylation · human · 12 samples
- What it is
- DNA methylationChemical marks on DNA that help switch genes on or off.
- Organism
- Homo sapiens (human)
- Samples
- 12 samples: 3 × NPC_IMP1_KD vs 3 × NPC_CTRL_KD vs 3 × Neuron_IMP1_KD vs 3 × Neuron_CTRL_KDGroups are read from the sample names, not from the paper. Check the list below.
- Data you can get
- A processed table (series matrix) and supplementary files from NCBI; the raw sequencing reads from ENA. Which of these hold counts depends on the study, so check the file list.
- Paper
- m6a methylation orchestrates IMP1 regulation of microtubules during human neuronal differentiationNature communications · 2024
Read the full summary ↓
Direct links to NCBI and ENA, no account and no request form. Pick by what you want to do: take the small processed table to look, the supplementary files to re-analyse, or the original raw data to start over.
Processed table
The series matrix: one table of values per sample as the submitters processed it. The smallest download, and it opens in Excel or R. Start here to see what the data look like.
Supplementary files
The count tables and other files the authors uploaded. Take only the samples you need, or the whole study as GSE203568_RAW.tar (it can run to tens of gigabytes).
Raw sequencing reads
The original FASTQ files, straight from the sequencer, held at ENA. Large, and you align them yourself, so only choose this if you need to re-process the study from scratch.
What the files usually look like: Look for beta-value tables or raw IDAT files among the supplementary files.
Also filed as BioProject PRJNA841468 and SRA study SRP376549. Searching any of these in the dataset finder brings you back here.
Supports a between-group comparison across 12 samples.
How we read this: 4 replicated groups read from 12 sample titles; they account for 12 of them. These groups are guessed from the sample names, not taken from the paper, so check them against the sample list below before relying on them.
- GSM6176367 NPC_IMP1_KD_biological_rep1 NPC_IMP1_KD
- GSM6176368 NPC_IMP1_KD_biological_rep2 NPC_IMP1_KD
- GSM6176369 NPC_IMP1_KD_biological_rep3 NPC_IMP1_KD
- GSM6176370 NPC_CTRL_KD_biological_rep1 NPC_CTRL_KD
- GSM6176371 NPC_CTRL_KD_biological_rep2 NPC_CTRL_KD
- GSM6176372 NPC_CTRL_KD_biological_rep3 NPC_CTRL_KD
- GSM6176373 Neuron_IMP1_KD_biological_rep1 Neuron_IMP1_KD
- GSM6176374 Neuron_IMP1_KD_biological_rep2 Neuron_IMP1_KD
- GSM6176375 Neuron_IMP1_KD_biological_rep3 Neuron_IMP1_KD
- GSM6176376 Neuron_CTRL_KD_biological_rep1 Neuron_CTRL_KD
- GSM6176377 Neuron_CTRL_KD_biological_rep2 Neuron_CTRL_KD
- GSM6176378 Neuron_CTRL_KD_biological_rep3 Neuron_CTRL_KD
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Metadata from NCBI GEO, cached and refreshed periodically — the NCBI page above is authoritative. Downloads link straight to NCBI/ENA; nothing is proxied through BioTransfer.