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Mouse mammary epithelial cell subpopulations from pregnant and virgin mice

GSE20402 Mus musculus Expression profiling by array 14 samples Submitted 2010/04/10 Platform GPL6887
Summary
To study the effect of pregnancy on mouse mammary epithelial subpopulations, epthelial cells derived from virgin or pregnant (12.5 day pregnant) mice were isolated using fluorescence-activated cell sorting. After elimination of haematopoietic and endothelial cells, two distinct epithelial subpopulations were sorted using antibodies against CD29 and CD24. Based on the immunohistochemical phenotype, and in vivo and in vitro functional assays, these subpopulations were identified as mammary stem cell enriched (CD29hiCD24+) and luminal (CD29loCD24+) respectively (ref: Shackleton et al, Nature 2006). Microarray profiling was used to compare gene expression profiles of the two subpopulations in 12.5 day pregnant and virgin mice.
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Also filed as BioProject PRJNA129829. Searching any of these in the dataset finder brings you back here.

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