Brain transcriptome analysis of Myt1l heterozygote mutation mice in different brain regions (RNA-Seq II)
RNA-seq (gene expression) · mouse · 34 samples
- What it is
- RNA-seq (gene expression)Gene activity measured by sequencing. The summary does not mention single-cell work, so this is most likely bulk: one average per sample, the usual starting point for comparing groups.
- Organism
- Mus musculus (mouse)
- Samples
- 34 samples: 6 conditions, mostly with about 6 replicates eachGroups are read from the sample names, not from the paper. Check the list below.
- Data you can get
- A processed table (series matrix) and supplementary files from NCBI; the raw sequencing reads from ENA. Which of these hold counts depends on the study, so check the file list.
- Paper
- Postnatal age-differential ASD-like transcriptomic, synaptic, and behavioral deficits in Myt1l-mutant miceCell reports · 2022
Read the full summary ↓
Direct links to NCBI and ENA, no account and no request form. Pick by what you want to do: take the small processed table to look, the supplementary files to re-analyse, or the original raw data to start over.
Processed table
The series matrix: one table of values per sample as the submitters processed it. The smallest download, and it opens in Excel or R. Start here to see what the data look like.
Supplementary files
The count tables and other files the authors uploaded. Take only the samples you need, or the whole study as GSE206714_RAW.tar (it can run to tens of gigabytes).
Raw sequencing reads
The original FASTQ files, straight from the sequencer, held at ENA. Large, and you align them yourself, so only choose this if you need to re-process the study from scratch.
What the files usually look like: For RNA-seq the counts are usually a table among the supplementary files (look for 'counts', 'expression', 'FPKM' or 'TPM' in the file name). The series matrix of a sequencing study is sometimes nearly empty.
Also filed as BioProject PRJNA851808 and SRA study SRP383138. Searching any of these in the dataset finder brings you back here.
Supports a between-group comparison across 34 samples.
How we read this: 6 replicated groups read from 34 sample titles; they account for 34 of them. These groups are guessed from the sample names, not taken from the paper, so check them against the sample list below before relying on them.
- GSM6261200 Myt1l prefrontal cortex-hetero 1 Myt1l prefrontal cortex…
- GSM6261201 Myt1l prefrontal cortex-hetero 2 Myt1l prefrontal cortex…
- GSM6261202 Myt1l prefrontal cortex-hetero 3 Myt1l prefrontal cortex…
- GSM6261203 Myt1l prefrontal cortex-hetero 4 Myt1l prefrontal cortex…
- GSM6261204 Myt1l prefrontal cortex-hetero 5 Myt1l prefrontal cortex…
- GSM6261205 Myt1l prefrontal cortex-wildtype 1 Myt1l prefrontal cortex…
- GSM6261206 Myt1l prefrontal cortex-wildtype 2 Myt1l prefrontal cortex…
- GSM6261207 Myt1l prefrontal cortex-wildtype 3 Myt1l prefrontal cortex…
- GSM6261208 Myt1l prefrontal cortex-wildtype 4 Myt1l prefrontal cortex…
- GSM6261209 Myt1l prefrontal cortex-wildtype 5 Myt1l prefrontal cortex…
- GSM6261210 Myt1l prefrontal cortex-wildtype 6 Myt1l prefrontal cortex…
- GSM6261211 Myt1l hippocampus-hetero 1 Myt1l hippocampus-hetero
- GSM6261212 Myt1l hippocampus-hetero 2 Myt1l hippocampus-hetero
- GSM6261213 Myt1l hippocampus-hetero 3 Myt1l hippocampus-hetero
- GSM6261214 Myt1l hippocampus-hetero 4 Myt1l hippocampus-hetero
- GSM6261215 Myt1l hippocampus-hetero 5 Myt1l hippocampus-hetero
- GSM6261216 Myt1l hippocampus-wildtype 1 Myt1l hippocampus-wildt…
- GSM6261217 Myt1l hippocampus-wildtype 2 Myt1l hippocampus-wildt…
- GSM6261218 Myt1l hippocampus-wildtype 3 Myt1l hippocampus-wildt…
- GSM6261219 Myt1l hippocampus-wildtype 4 Myt1l hippocampus-wildt…
- GSM6261220 Myt1l hippocampus-wildtype 5 Myt1l hippocampus-wildt…
- GSM6261221 Myt1l hippocampus-wildtype 6 Myt1l hippocampus-wildt…
- GSM6261222 Myt1l striatum-hetero 1 Myt1l striatum-hetero
- GSM6261223 Myt1l striatum-hetero 2 Myt1l striatum-hetero
- GSM6261224 Myt1l striatum-hetero 3 Myt1l striatum-hetero
- GSM6261225 Myt1l striatum-hetero 4 Myt1l striatum-hetero
- GSM6261226 Myt1l striatum-hetero 5 Myt1l striatum-hetero
- GSM6261227 Myt1l striatum-hetero 6 Myt1l striatum-hetero
- GSM6261228 Myt1l striatum-wildtype 1 Myt1l striatum-wildtype
- GSM6261229 Myt1l striatum-wildtype 2 Myt1l striatum-wildtype
- GSM6261230 Myt1l striatum-wildtype 3 Myt1l striatum-wildtype
- GSM6261231 Myt1l striatum-wildtype 4 Myt1l striatum-wildtype
- GSM6261232 Myt1l striatum-wildtype 5 Myt1l striatum-wildtype
- GSM6261233 Myt1l striatum-wildtype 6 Myt1l striatum-wildtype
- GSE318815 Differential sex-dependent responses of circulating steroid hormones and cortical gene expression in a preclinical traumatic brain injury model 88 samples shares different, brain
- GSE334845 Discovery of Tcf7 regulators with clonally-resolved CRISPR screens identifies Trim28 as a mediator of CD8 T cell differentiation in tumors [RNA-Seq] 86 samples shares different, rna-seq
- GSE310017 Disease-associated mutations on the STAT5B SH2 domain regulate cholesterol and lipid metabolism in liver [RNA-Seq liver] 37 samples shares mutation, rna-seq
- GSE244320 RNA-sequencing analysis of colon RNA from mice with compound mutations of XBP1, caspase-8, TNFR1 and MLKL. 30 samples shares mutation, rna-seq
- GSE325329 Transcriptomic profiling of macrophages that phagocytosed apoptotic Treg or conventional CD4⁺ T (Tconv) cells under different polarization conditions [RNA-Seq] 28 samples shares different, rna-seq
- GSE239469 Condensate-promoting ENL mutation induces tumorigenesis via chromatin remodeling [RNA-seq] 28 samples shares mutation, rna-seq
- GSE267967 Foxp3 and BATF cooperatively direct cis-regulatory programs and gene expression for functional differentiation of Treg cells [RNA-seq] 26 samples shares different, rna-seq
- GSE267688 Autism-associated mutations in Kdm6b affect its role as a chromatin regulator in brain development 20 samples shares mutation, brain
Metadata from NCBI GEO, cached and refreshed periodically — the NCBI page above is authoritative. Downloads link straight to NCBI/ENA; nothing is proxied through BioTransfer.