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Transcriptomes in Human neuroblastoma cell line SH-SY5Y depleted with ERRαlpha and ERRgamma

GSE208270 Homo sapiens Expression profiling by high throughput sequencing 7 samples Submitted 2024/08/20 Platform GPL28038
Summary
The SH-SY5Y Human neuroblastoma cell line was subcloned from the SK-N-SH cell line, which has been isolated from a bone marrow biopsy of a 4 year-old female patient. To examine the overall distribution of gene expression under stress condition in human neuronal cells, we investigated changes in the transcriptome profiles in the SH-SY5Y cells depleted with ERRαlpha and ERRgamma by gene knockdown. We detected changes in the expression levels for several genes.
Published in
ERRα and ERRγ coordinate expression of genes associated with Alzheimer's disease, inhibiting DKK1 to suppress tau phosphorylation
Sato K, Takayama KI, Saito Y et al. · Proceedings of the National Academy of Sciences of the United States of America 2024 · PMID 39231208 · doi:10.1073/pnas.2406854121
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Also filed as BioProject PRJNA858482 and SRA study SRP386325. Searching any of these in the dataset finder brings you back here.

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