GEO series
Epigenetic Control over IFN Type-I Response antagonizes self-renewal in acute myeloid leukemia (RNA-seq)
GSE211642
Homo sapiens
Expression profiling by high throughput sequencing
18 samples
2024/03/11
GPL18573
Summary
To investigate the impact of PHF8 demethylase activity and PHF8 phosphorylation changes in blocking AML cells progression. We established THP1-wt, THP1-PHF8 and THP1-F279S cell lines for demethylase activity studies and THP1-PHF8AA and THP1-PHF8DD for phosphorylation studies.
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Paper (PMID 38457355) ↗
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