Effect of Simvastatin on endothelial cells
ChIP-seq / ATAC-seq (genome binding and open chromatin) · human · 18 samples
- What it is
- ChIP-seq / ATAC-seq (genome binding and open chromatin)Where proteins bind the genome, or which regions are open and active.
- Organism
- Homo sapiens (human)
- Samples
- 18 samples: 8 conditions, mostly in duplicateGroups are read from the sample names, not from the paper. Check the list below.
- Data you can get
- A processed table (series matrix) and supplementary files from NCBI; the raw sequencing reads from ENA. Which of these hold counts depends on the study, so check the file list.
Direct links to NCBI and ENA, no account and no request form. Pick by what you want to do: take the small processed table to look, the supplementary files to re-analyse, or the original raw data to start over.
Processed table
The series matrix: one table of values per sample as the submitters processed it. The smallest download, and it opens in Excel or R. Start here to see what the data look like.
Supplementary files
The count tables and other files the authors uploaded. Take only the samples you need, or the whole study as GSE212880_RAW.tar (it can run to tens of gigabytes).
Raw sequencing reads
The original FASTQ files, straight from the sequencer, held at ENA. Large, and you align them yourself, so only choose this if you need to re-process the study from scratch.
What the files usually look like: Look for peak files (.bed, .narrowPeak) and signal tracks (.bigWig) among the supplementary files; the raw reads are on ENA.
Also filed as BioProject PRJNA877683 and SRA study SRP396111. Searching any of these in the dataset finder brings you back here.
Supports a between-group comparison across 16 samples.
How we read this: 8 replicated groups read from 18 sample titles; they account for 16 of them. These groups are guessed from the sample names, not taken from the paper, so check them against the sample list below before relying on them.
- GSM6560454 iEC, control, rep1 iEC, control,
- GSM6560455 iEC, control, rep2 iEC, control,
- GSM6560456 iEC, dia, rep1 iEC, dia,
- GSM6560457 iEC, dia, rep2 iEC, dia,
- GSM6560458 iEC, sim,12h, rep1
- GSM6560459 iEC, sim, 12h, rep2
- GSM6560460 iEC, sim, 24h, rep1 iEC, sim, 24h,
- GSM6560461 iEC, sim, 24h, rep2 iEC, sim, 24h,
- GSM6560462 iEC, sim, 72h, rep1 iEC, sim, 72h,
- GSM6560463 iEC, sim, 72h, rep2 iEC, sim, 72h,
- GSM6560464 heart, control, rep1 heart, control,
- GSM6560465 heart, control, rep2 heart, control,
- GSM6560466 heart, dia, rep1 heart, dia,
- GSM6560467 heart, dia, rep2 heart, dia,
- GSM6560468 heart, sim, rep1 heart, sim,
- GSM6560469 heart, sim, rep2 heart, sim,
- GSM6560470 heart, ggti, rep1 heart, ggti,
- GSM6560471 heart, ggti, rep2 heart, ggti,
- GSE312663 IL-9 in psoriasis: human endothelial cells and murine T cells 18 samples shares endothelial
- GSE195453 Identification of the endothelial cell microproteome. 121 samples shares endothelial
- GSE285730 Targeting PARK7: Sodium 4-Phenylbutyrate Shields Endothelial Cells from GSDME-Mediated Pyroptosis in Acute Lung Injury 15 samples shares endothelial
- GSE47067 In Vivo Endothelial Cell Heterogeneity 57 samples shares endothelial
- GSE270175 Oxysterol Sensing through GPR183 Triggers Endothelial Senescence and Cardio-renal Injuries via Altering Circadian Signaling in Hypertension 18 samples shares endothelial
- GSE300885 Endothelial PIEZO1 activation impairs osteogenesis via GREM1-mediated inhibition of BMP signaling 16 samples shares endothelial
- GSE309462 Endothelial BMP6 Drives Hemodynamic-Dependent VSMCs Calcification in Carotid Atherosclerosis 14 samples shares endothelial
- GSE250618 Human liver sinusoidal endothelial cells support the development of functional human pluripotent stem cell-derived Kupffer cells 1 samples shares endothelial
Metadata from NCBI GEO, cached and refreshed periodically — the NCBI page above is authoritative. Downloads link straight to NCBI/ENA; nothing is proxied through BioTransfer.