The histone H3 lysine 36 demethylase KDM2A/FBXL11 is essential for germ cell development in male mice [RNA-Seq]
RNA-seq (gene expression) · mouse · 24 samples
- What it is
- RNA-seq (gene expression)Gene activity measured by sequencing. The summary does not mention single-cell work, so this is most likely bulk: one average per sample, the usual starting point for comparing groups.
- Organism
- Mus musculus (mouse)
- Samples
- 24 samples
- Data you can get
- A processed table (series matrix) and supplementary files from NCBI; the raw sequencing reads from ENA. Which of these hold counts depends on the study, so check the file list.
- Paper
- The histone H3 lysine 36 demethylase KDM2A/FBXL11 controls Polycomb-mediated gene repression and germ cell development in male miceNature communications · 2025
Read the full summary ↓
Direct links to NCBI and ENA, no account and no request form. Pick by what you want to do: take the small processed table to look, the supplementary files to re-analyse, or the original raw data to start over.
Processed table
The series matrix: one table of values per sample as the submitters processed it. The smallest download, and it opens in Excel or R. Start here to see what the data look like.
Supplementary files
The count tables and other files the authors uploaded. Take only the samples you need, or the whole study as GSE214680_RAW.tar (it can run to tens of gigabytes).
Raw sequencing reads
The original FASTQ files, straight from the sequencer, held at ENA. Large, and you align them yourself, so only choose this if you need to re-process the study from scratch.
What the files usually look like: For RNA-seq the counts are usually a table among the supplementary files (look for 'counts', 'expression', 'FPKM' or 'TPM' in the file name). The series matrix of a sequencing study is sometimes nearly empty.
Also filed as BioProject PRJNA886676 and SRA study SRP400801. Searching any of these in the dataset finder brings you back here.
The sample list for this study is not cached yet. Press Load samples and it will be fetched from NCBI.
+ 24 more — browse all 24 samples with per-sample file links →
- GSE214682 The histone H3 lysine 36 demethylase KDM2A/FBXL11 is essential for germ cell development in male mice 56 samples shares fbxl11, kdm2a, demethylase, essential, histone, lysine, germ
- GSE294512 eIF4G2-mediated Translation Initiation of Histone Modifiers is Essential for Intestinal Stem Cell Maintenance and Differentiation [RNA-seq] 92 samples shares essential, histone, rna-seq
- GSE262866 The histone demethylase KDM5C regulates IRF transcriptional programming impacting dendritic cell population heterogeneity and function (RNA-seq) 55 samples shares demethylase, histone, rna-seq
- GSE291446 T cell receptor signaling induces expression of lysine demethylase KDM6B to maintain Treg homeostasis [RNA-seq] 20 samples shares demethylase, rna-seq, lysine
- GSE276730 The histone lysine demethylase KDM7A contributes to reward memory via Fscn1-induced synaptic plasticity in the medial prefrontal cortex 16 samples shares demethylase, histone, lysine
- GSE311802 Autism-like phenotypes and increased NMDAR2D expression in mice with KDM5B histone lysine demethylase deficiency 16 samples shares demethylase, histone, lysine
- GSE286398 Lysine-specific demethylase 1 regulates hematopoietic stem cell expansion and myeloid cell differentiation [scRNA-seq] 13 samples shares demethylase, rna-seq, lysine
- GSE223673 Nr5a2 is dispensable for ZGA but essential for morula development [RNA-seq] 514 samples shares essential, rna-seq
Metadata from NCBI GEO, cached and refreshed periodically — the NCBI page above is authoritative. Downloads link straight to NCBI/ENA; nothing is proxied through BioTransfer.