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Twist family BHLH transcription factor 1 is required for the maintenance of leukemia stem cell in MLL-AF9+ acute myeloid leukemia

GSE215026 Mus musculus Expression profiling by high throughput sequencing 4 samples Submitted 2025/10/06 Platform GPL21103
Summary
To identify the downstream targets of TWIST1 or Hoxa9, we carried out RNA sequencing to characterize transcriptional changes upon Twist1 deletion or Hoxa9 knockdown in LSCs from MLL-AF9+ AML mice.
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Twist family BHLH transcription factor 1 is required for the maintenance of leukemia stem cell in MLL-AF9(+) acute myeloid leukemia
Wang N, Yin J, You N et al. · Haematologica 2024 · PMID 37767575 · doi:10.3324/haematol.2023.282748
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Also filed as BioProject PRJNA888092 and SRA study SRP401519. Searching any of these in the dataset finder brings you back here.

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