GEO series
Identification of Whole Blood Gene Expression Signature to Predict the Therapeutic Effect of Nintedanib in Idiopathic Pulmonary Fibrosis
GSE215274
Homo sapiens
Expression profiling by high throughput sequencing
177 samples
2025/10/11
GPL18573
Summary
We aimed to determine gene expression signature associated with the therapeutic effect of nintedanib in patients with IPF using whole blood cells. A total of 87 IPF patients treated with nintedanib were prospectively analysed in this study. RNA from whole blood cells was collected from all patients at enrollment (0M), 3 months (3M) after treatment with nintedanib, and/or at the onset of an acute exacerbation (AE). We then performed gene expression profiling analysis using data obtained from RNA-seq.
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