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Identification of p53 target genes in various tissues and organs using Cut&tag

GSE217404 Mus musculus Genome binding/occupancy profiling by high throughput sequencing 60 samples 2025/09/10 GPL28330
Summary
For decades, researchers have devoted great efforts to study the tumor suppressor gene Trp53. However, tissue-specific Trp53 regulation still remains elusive.Here, we used Cut&tag to analyze the p53 target gene groups in 18 tissues and organs of adult mice to decipher the tissue heterogeneity of Trp53 regulation.
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