Androgen receptor action in mouse granulosa cells in response to LH surge
ChIP-seq / ATAC-seq (genome binding and open chromatin) · mouse · 14 samples
- What it is
- ChIP-seq / ATAC-seq (genome binding and open chromatin)Where proteins bind the genome, or which regions are open and active.
- Organism
- Mus musculus (mouse)
- Samples
- 14 samples: 4 × PGRWT, PMSG, AR, vs 4 × PGRWT, hCG, AR, vs 4 × PGRKO, hCG, AR,Groups are read from the sample names, not from the paper. Check the list below.
- Data you can get
- A processed table (series matrix) and supplementary files from NCBI; the raw sequencing reads from ENA. Which of these hold counts depends on the study, so check the file list.
Read the full summary ↓
Direct links to NCBI and ENA, no account and no request form. Pick by what you want to do: take the small processed table to look, the supplementary files to re-analyse, or the original raw data to start over.
Processed table
The series matrix: one table of values per sample as the submitters processed it. The smallest download, and it opens in Excel or R. Start here to see what the data look like.
Supplementary files
The count tables and other files the authors uploaded. Take only the samples you need, or the whole study as GSE249984_RAW.tar (it can run to tens of gigabytes).
Raw sequencing reads
The original FASTQ files, straight from the sequencer, held at ENA. Large, and you align them yourself, so only choose this if you need to re-process the study from scratch.
What the files usually look like: Look for peak files (.bed, .narrowPeak) and signal tracks (.bigWig) among the supplementary files; the raw reads are on ENA.
Also filed as BioProject PRJNA1051553 and SRA study SRP477559. Searching any of these in the dataset finder brings you back here.
Supports a between-group comparison across 12 samples.
How we read this: 3 replicated groups read from 14 sample titles; they account for 12 of them. These groups are guessed from the sample names, not taken from the paper, so check them against the sample list below before relying on them.
- GSM7968448 PGRWT, PMSG, AR, rep1 PGRWT, PMSG, AR,
- GSM7968449 PGRWT, PMSG, AR, rep2 PGRWT, PMSG, AR,
- GSM7968450 PGRWT, PMSG, AR, rep3 PGRWT, PMSG, AR,
- GSM7968451 PGRWT, PMSG, AR, rep4 PGRWT, PMSG, AR,
- GSM7968452 PGRWT, hCG, AR, rep1 PGRWT, hCG, AR,
- GSM7968453 PGRWT, hCG, AR, rep2 PGRWT, hCG, AR,
- GSM7968454 PGRWT, hCG, AR, rep3 PGRWT, hCG, AR,
- GSM7968455 PGRWT, hCG, AR, rep4 PGRWT, hCG, AR,
- GSM7968456 PGRKO, hCG, AR, rep1 PGRKO, hCG, AR,
- GSM7968457 PGRKO, hCG, AR, rep2 PGRKO, hCG, AR,
- GSM7968458 PGRKO, hCG, AR, rep3 PGRKO, hCG, AR,
- GSM7968459 PGRKO, hCG, AR, rep4 PGRKO, hCG, AR,
- GSM7968460 AR pooled input, rep1 rep2
- GSM7968461 AR pooled input, rep3 rep4
- GSE249985 Glucocorticoid receptor action in mouse granulosa cells in response to LH surge 9 samples shares granulosa, receptor, action, surge
- GSE255212 Transcriptomic Signatures of WNT-Driven Pathways and Granulosa Cell-Oocyte Interaction during Primordial Follicle Activation 762 samples shares granulosa, action
- GSE285574 Foxa1 mutations co-opt nascent transcription factor networks in partnership with androgen receptor to enhance prostate tumorigenicity 38 samples shares androgen, receptor
- GSE316048 A Receptor-Clamped IL-2 Uncouples Treg Expansion from Injection Site Reactions 24 samples shares receptor, action
- GSE236551 Non-canonical hepatic androgen receptor mediates glucagon sensitivity in female mice through the PGC1α/ERRα/mitochondria axis 12 samples shares androgen, receptor
- GSE316171 Fibroblast Growth Factor Receptor Signaling in Maturing Osteoblasts Controls Cell-Matrix Interactions Critical for Osteocyte Survival 8 samples shares receptor, action
- GSE326173 Nuclear receptor Nur77 resolves the inflammatory response of macrophages primarily by regulating expression of AP-1 transcription factors and their target genes [ChIP-seq] 42 samples shares receptor
- GSE281498 The transcription factor BATF pioneers the differentiation program of cytolytic effector CD8+ T cells through the direct interaction with IRF4 (ATAC-seq) 20 samples shares action
Metadata from NCBI GEO, cached and refreshed periodically — the NCBI page above is authoritative. Downloads link straight to NCBI/ENA; nothing is proxied through BioTransfer.