Exploring the potential mechanism of artesunate in intervening with glioma cells with distinct therapeutic effects on the basis of transcriptome sequencing and network pharmacology
RNA-seq (gene expression) · human · 12 samples
- What it is
- RNA-seq (gene expression)Gene activity measured by sequencing. The summary does not mention single-cell work, so this is most likely bulk: one average per sample, the usual starting point for comparing groups.
- Organism
- Homo sapiens (human)
- Samples
- 12 samples: 3 × U251 vs 3 × U251-ART vs 3 × U87 vs 3 × U87-ARTGroups are read from the sample names, not from the paper. Check the list below.
- Data you can get
- A processed table (series matrix) and supplementary files from NCBI; the raw sequencing reads from ENA. Which of these hold counts depends on the study, so check the file list.
Read the full summary ↓
Direct links to NCBI and ENA, no account and no request form. Pick by what you want to do: take the small processed table to look, the supplementary files to re-analyse, or the original raw data to start over.
Processed table
The series matrix: one table of values per sample as the submitters processed it. The smallest download, and it opens in Excel or R. Start here to see what the data look like.
Supplementary files
The count tables and other files the authors uploaded. Take only the samples you need, or the whole study as GSE217531_RAW.tar (it can run to tens of gigabytes).
Raw sequencing reads
The original FASTQ files, straight from the sequencer, held at ENA. Large, and you align them yourself, so only choose this if you need to re-process the study from scratch.
What the files usually look like: For RNA-seq the counts are usually a table among the supplementary files (look for 'counts', 'expression', 'FPKM' or 'TPM' in the file name). The series matrix of a sequencing study is sometimes nearly empty.
Also filed as BioProject PRJNA899484 and SRA study SRP406839. Searching any of these in the dataset finder brings you back here.
Supports a between-group comparison across 12 samples.
How we read this: 4 replicated groups read from 12 sample titles; they account for 12 of them. These groups are guessed from the sample names, not taken from the paper, so check them against the sample list below before relying on them.
- GSM6721098 U251-1 U251
- GSM6721099 U251-2 U251
- GSM6721100 U251-3 U251
- GSM6721101 U251-ART-1 U251-ART
- GSM6721102 U251-ART-2 U251-ART
- GSM6721103 U251-ART-3 U251-ART
- GSM6721104 U87-1 U87
- GSM6721105 U87-2 U87
- GSM6721106 U87-3 U87
- GSM6721107 U87-ART-1 U87-ART
- GSM6721108 U87-ART-2 U87-ART
- GSM6721109 U87-ART-3 U87-ART
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- GSE273036 Multi-Omics Analysis and Molecular Subtypes Provide Potential Therapeutic Implications in Fumarate Hydratase-deficient Renal Cell Carcinoma 93 samples shares therapeutic, potential
- GSE335924 RNA-seq Identifies FOS as a Potential Therapeutic Target Activating Neural Stem Cells via miR-21/SOX2 Pathway in Hypertensive Intracerebral Hemorrhage 53 samples shares therapeutic, potential
- GSE277715 The Proteostasis Network is a Therapeutic Target in Acute Myeloid Leukemia 36 samples shares therapeutic, network
- GSE232862 Effect of Terpenes from Poria Cocos: Verification of Therapeutic Modes of Action for Alzheimer’s Disease using Molecular Docking, Drug-induced Transcriptomes and Diffusion Network 18 samples shares therapeutic, network
- GSE245935 Chemo-senolytic therapeutic potential against angiosarcoma 13 samples shares therapeutic, potential
- GSE269942 YAP1 status defines two intrinsic subtypes of LCNEC with distinct molecular features and therapeutic vulnerabilities 12 samples shares therapeutic, distinct
- GSE317656 Erastin-Induced Ferroptosis Enhances Natural Killer Cell Anti-Tumor Activity and Offers Therapeutic Potential in Neuroblastoma 12 samples shares therapeutic, potential
Metadata from NCBI GEO, cached and refreshed periodically — the NCBI page above is authoritative. Downloads link straight to NCBI/ENA; nothing is proxied through BioTransfer.