Expression data throughout reprogramming of MEF to iPS using a Dox-inducible promoter
Expression microarray · mouse · 13 samples
- What it is
- Expression microarrayGene activity read on a chip (the older technology that RNA-seq replaced).
- Organism
- Mus musculus (mouse)
- Samples
- 13 samples: 7 × 6C-Secondary - day vs 2 × 1B-Secondary - dayGroups are read from the sample names, not from the paper. Check the list below.
- Data you can get
- A processed expression table (series matrix) and the array files, from NCBI.
Direct links to NCBI, no account and no request form. Pick by what you want to do: take the small processed table to look, the supplementary files to re-analyse, or the original raw data to start over.
Processed table
The series matrix: one table of values per sample as the submitters processed it. The smallest download, and it opens in Excel or R. Start here to see what the data look like.
Supplementary files
The count tables and other files the authors uploaded. Take only the samples you need.
Whole study · RAW.tar
Everything the authors deposited as one archive (GSE21757_RAW.tar), including the raw array or instrument files. Can be large; the picker in step 2 takes just the samples you need.
What the files usually look like: For arrays the series matrix is normally the normalised expression table you want; the raw array files (CEL and similar) are in the RAW.tar.
Also filed as BioProject PRJNA127267. Searching any of these in the dataset finder brings you back here.
Supports a between-group comparison across 9 samples.
How we read this: 2 replicated groups read from 13 sample titles; they account for 9 of them. These groups are guessed from the sample names, not taken from the paper, so check them against the sample list below before relying on them.
- GSM542374 Parental MEF cells
- GSM542375 6C-Secondary - day0 6C-Secondary - day
- GSM542376 6C-Secondary - day2 6C-Secondary - day
- GSM542377 6C-Secondary - day5 6C-Secondary - day
- GSM542378 6C-Secondary - day8 6C-Secondary - day
- GSM542379 6C-Secondary - day11 6C-Secondary - day
- GSM542380 6C-Secondary - day16 6C-Secondary - day
- GSM542381 6C-Secondary - day21 6C-Secondary - day
- GSM542382 6C-Secondary - iPS
- GSM542383 6C-Primary - iPS
- GSM542384 1B-Secondary - day0 1B-Secondary - day
- GSM542385 1B-Secondary - day5 1B-Secondary - day
- GSM542386 1B-Secondary - day5w, day5w/o
- GSE295582 Sirtuin 7 regulates dosage compensation and safeguards the female X-chromosome [ChIP_H2AX_gH2AX_MEF] 24 samples shares mef
- GSE295586 Sirtuin 7 regulates dosage compensation and safeguards the female X-chromosome [RNA-seq_male_female_MEF] 12 samples shares mef
- GSE22292 Gene expression in mouse neonatal cardiomyocytes, cardiac fibroblasts, reprogramming failed GFP- cells, and GFP+ iCMs 18 samples shares reprogramming
- GSE10806 Pluripotent stem cells induced from adult neural stem cells by reprogramming with two factors 11 samples shares reprogramming
- GSE261698 A glial circadian gene expression atlas reveals cell type and disease-specific reprogramming in response to amyloid pathology or aging 165 samples shares reprogramming
- GSE268822 Transcriptional landscapes underlying Notch-induced lineage conversion and reprogramming of mammary cells 840 samples shares reprogramming
- GSE222745 Enhanced activities of OCT4 and SOX2 facilitates epigenetic reprogramming by modulating cell cycle [scRNA-Seq] 422 samples shares reprogramming
- GSE269318 Cancer-intrinsic Cxcl5 orchestrates global metabolic reprogramming of three dimensional cancers by upregulating Hif1α and Myc expression 31 samples shares reprogramming
Metadata from NCBI GEO, cached and refreshed periodically — the NCBI page above is authoritative. Downloads link straight to NCBI/ENA; nothing is proxied through BioTransfer.