To determine the global gene expression response in murine LPS-induced macrophages treated with a bromodomain inhibitor.
Expression microarray · mouse · 24 samples
- What it is
- Expression microarrayGene activity read on a chip (the older technology that RNA-seq replaced).
- Organism
- Mus musculus (mouse)
- Samples
- 24 samples: 8 conditions, mostly in triplicateGroups are read from the sample names, not from the paper. Check the list below.
- Data you can get
- A processed expression table (series matrix) and the array files, from NCBI.
Read the full summary ↓
Direct links to NCBI, no account and no request form. Pick by what you want to do: take the small processed table to look, the supplementary files to re-analyse, or the original raw data to start over.
Processed table
The series matrix: one table of values per sample as the submitters processed it. The smallest download, and it opens in Excel or R. Start here to see what the data look like.
Supplementary files
The count tables and other files the authors uploaded. Take only the samples you need.
Whole study · RAW.tar
Everything the authors deposited as one archive (GSE21764_RAW.tar), including the raw array or instrument files. Can be large; the picker in step 2 takes just the samples you need.
What the files usually look like: For arrays the series matrix is normally the normalised expression table you want; the raw array files (CEL and similar) are in the RAW.tar.
Also filed as BioProject PRJNA127281. Searching any of these in the dataset finder brings you back here.
Supports a between-group comparison across 24 samples.
How we read this: 8 replicated groups read from 24 sample titles; they account for 24 of them. These groups are guessed from the sample names, not taken from the paper, so check them against the sample list below before relying on them.
- GSM542464 0hr_LPS_control_rep1 0hr_LPS_control
- GSM542465 0hr_LPS_BET treat_rep1 0hr_LPS_BET treat
- GSM542466 1hr_LPS_control_rep1 1hr_LPS_control
- GSM542467 1hr_LPS_BET treat_rep1 1hr_LPS_BET treat
- GSM542468 2hr_LPS_control_rep1 2hr_LPS_control
- GSM542469 2hr_LPS_BET treat_rep1 2hr_LPS_BET treat
- GSM542470 4hr_LPS_control_rep1 4hr_LPS_control
- GSM542471 4hr_LPS_BET treat_rep1 4hr_LPS_BET treat
- GSM542472 0hr_LPS_control_rep2 0hr_LPS_control
- GSM542473 0hr_LPS_BET treat_rep2 0hr_LPS_BET treat
- GSM542474 1hr_LPS_control_rep2 1hr_LPS_control
- GSM542475 1hr_LPS_BET treat_rep2 1hr_LPS_BET treat
- GSM542476 2hr_LPS_control_rep2 2hr_LPS_control
- GSM542477 2hr_LPS_BET treat_rep2 2hr_LPS_BET treat
- GSM542478 4hr_LPS_control_rep2 4hr_LPS_control
- GSM542479 4hr_LPS_BET treat_rep2 4hr_LPS_BET treat
- GSM542480 0hr_LPS_control_rep3 0hr_LPS_control
- GSM542481 0hr_LPS_BET treat_rep3 0hr_LPS_BET treat
- GSM542482 1hr_LPS_control_rep3 1hr_LPS_control
- GSM542483 1hr_LPS_BET treat_rep3 1hr_LPS_BET treat
- GSM542484 2hr_LPS_control_rep3 2hr_LPS_control
- GSM542485 2hr_LPS_BET treat_rep3 2hr_LPS_BET treat
- GSM542486 4hr_LPS_control_rep3 4hr_LPS_control
- GSM542487 4hr_LPS_BET treat_rep3 4hr_LPS_BET treat
- GSE201128 The response to lipopolysaccharide (LPS) of bone marrow derived macrophages treated with oxysterol binding protein (OSBP) inhibitors 30 samples shares macrophages, inhibitor, treated
- GSE325662 Gene expression profiling of lung tissue from LPS-induced acute lung injury mice treated with Renshen Baidu Powder 9 samples shares lps-induced, treated
- GSE249970 Transcriptome analysis of lung derived from LPS-induced ARDS model mice treated with EVs or SPLEVs. 4 samples shares lps-induced, treated
- GSE270915 The expression order determines the pioneer functions of Ngn3 and NeuroD1 in pancreatic endocrine differentiation 3745 samples shares determine
- GSE72539 CTCF binding polarity determines chromatin looping [4C] 504 samples shares determine
- GSE268774 Lymph node macrophages drive immune tolerance and resistance to cancer therapy by expression of the immune-regulatory cytokine IL-33 [RNA-seq] 48 samples shares macrophages
- GSE300925 Lyn expression in macrophages promotes TLR activation and restricts proliferation in an isoform-independent manner 48 samples shares macrophages
- GSE326173 Nuclear receptor Nur77 resolves the inflammatory response of macrophages primarily by regulating expression of AP-1 transcription factors and their target genes [ChIP-seq] 42 samples shares macrophages
Metadata from NCBI GEO, cached and refreshed periodically — the NCBI page above is authoritative. Downloads link straight to NCBI/ENA; nothing is proxied through BioTransfer.