GEO series
Anti-CD25 Treg targeting antibodies sparing IL-2 signaling promote regression of established glioblastoma tumors and innate cell activation.
GSE218013
Mus musculus
Expression profiling by high throughput sequencing
16 samples
2025/05/12
GPL24247
Summary
Treg depletion in mouse GBM using the anti-CD25 antibody, led to tumor regression and improved survival. We performed single cell RNA sequencing on tumor, lymphoid and myeloid samples from treated and untreated samples
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Paper (PMID 40280128) ↗
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