Paternal exposure alone induces alcohol-related birth defects in a mouse model: Implications of paternal drinking in FAS birth defects.
RNA-seq (gene expression) · mouse · 16 samples
- What it is
- RNA-seq (gene expression)Gene activity measured by sequencing. The summary does not mention single-cell work, so this is most likely bulk: one average per sample, the usual starting point for comparing groups.
- Organism
- Mus musculus (mouse)
- Samples
- 16 samples: 8 conditions, mostly in duplicateGroups are read from the sample names, not from the paper. Check the list below.
- Data you can get
- A processed table (series matrix) and supplementary files from NCBI; the raw sequencing reads from ENA. Which of these hold counts depends on the study, so check the file list.
Read the full summary ↓
Direct links to NCBI and ENA, no account and no request form. Pick by what you want to do: take the small processed table to look, the supplementary files to re-analyse, or the original raw data to start over.
Processed table
The series matrix: one table of values per sample as the submitters processed it. The smallest download, and it opens in Excel or R. Start here to see what the data look like.
Supplementary files
The count tables and other files the authors uploaded. Take only the samples you need, or the whole study as GSE218362_RAW.tar (it can run to tens of gigabytes).
Raw sequencing reads
The original FASTQ files, straight from the sequencer, held at ENA. Large, and you align them yourself, so only choose this if you need to re-process the study from scratch.
What the files usually look like: For RNA-seq the counts are usually a table among the supplementary files (look for 'counts', 'expression', 'FPKM' or 'TPM' in the file name). The series matrix of a sequencing study is sometimes nearly empty.
Also filed as BioProject PRJNA903218. Searching any of these in the dataset finder brings you back here.
Supports a between-group comparison across 16 samples.
How we read this: 8 replicated groups read from 16 sample titles; they account for 16 of them. These groups are guessed from the sample names, not taken from the paper, so check them against the sample list below before relying on them.
- GSM6742913 Male Cortex, Control, rep1 Male Cortex, Control,
- GSM6742914 Male Cortex, Control, rep2 Male Cortex, Control,
- GSM6742915 Male Cortex, PaternalExp, rep1 Male Cortex, PaternalEx…
- GSM6742916 Male Cortex, PaternalExp, rep2 Male Cortex, PaternalEx…
- GSM6742917 Male Cortex, MaternalExp, rep1 Male Cortex, MaternalEx…
- GSM6742918 Male Cortex, MaternalExp, rep2 Male Cortex, MaternalEx…
- GSM6742919 Male Cortex, DualExp, rep1 Male Cortex, DualExp,
- GSM6742920 Male Cortex, DualExp, rep2 Male Cortex, DualExp,
- GSM6742921 Female Cortex, Control, rep1 Female Cortex, Control,
- GSM6742922 Female Cortex, Control, rep2 Female Cortex, Control,
- GSM6742923 Female Cortex, PaternalExp, rep1 Female Cortex, Paternal…
- GSM6742924 Female Cortex, PaternalExp, rep2 Female Cortex, Paternal…
- GSM6742925 Female Cortex, MaternalExp, rep1 Female Cortex, Maternal…
- GSM6742926 Female Cortex, MaternalExp, rep2 Female Cortex, Maternal…
- GSM6742927 Female Cortex, DualExp, rep1 Female Cortex, DualExp,
- GSM6742928 Female Cortex, DualExp, rep2 Female Cortex, DualExp,
- GSE263158 Exposure of Ldlr-/- mice to a PFAS mixture increased circulating cholesterol and decreased bile acid excretion with concurrent increases in male ileal ASBT 20 samples shares fas, exposure
- GSE303480 Broad Profiling of Hepatic and Immunotoxic Effects of Per- and Polyfluoroalkyl Substances (PFASs) Across Sexes and Exposure Durations in C57/BL6 Mice 116 samples shares fas, exposure
- GSE300410 Parental preconceptual α-cypermethrin exposure alters embryonic brain transcriptomics in mice: implications for autism spectrum disorder and stress vulnerability 76 samples shares implications, exposure
- GSE290224 Intermittent Fasting Reprograms Chromatin Accessibility to Modulate Gene Expression in Brain and Muscle 96 samples shares fas
- GSE328655 A high-resolution, sex-stratified atlas of transcriptional and alternative splicing dynamics in the fasting mouse liver. 80 samples shares fas
- GSE246617 Cerebral vascular transcriptome profiling reveals intermittent fasting modulates chronic cerebral hypoperfusion-induced disease pathways. 78 samples shares fas
- GSE186649 A mitochondrial long-chain fatty acid oxidation defect in a mouse leads to dysregulation of plasma long-chain acylcarnitines, dysregulation of plasma amino acids, and an increased reliance on glucocorticoid signaling to maintain euglycemia during fasting 50 samples shares fas
- GSE282292 Sexually dimorphic effects of CYP2B6 in the development of fasting-mediated steatosis in mice: Effects are not mediated by the oxylipin products 9-HODE and 9-HOTrE 44 samples shares fas
Metadata from NCBI GEO, cached and refreshed periodically — the NCBI page above is authoritative. Downloads link straight to NCBI/ENA; nothing is proxied through BioTransfer.