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Tumor cell intrinsic RIG-I activation is sufficient to drive immune mediated tumor rejection

GSE221564 Mus musculus Expression profiling by high throughput sequencing 14 samples 2025/11/28 GPL17021
Summary
Tumor microenvironment (TME) is key in cancer development. Rencently strategies focus on activation of the innate immune response to enhance the immunesurveillance. Here, we analyse how activation of the nucleic acid sensor RIG-I modifies the tumor cells transcriptome.
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